Results 41 to 50 of about 21,735 (118)

Neuron Signal Propagation Analysis of Cytokine-Storm induced Demyelination [PDF]

arXiv, 2021
The COVID-19 pandemic has shaken the world unprecedentedly, where it has affected the vast global population both socially and economically. The pandemic has also opened our eyes to the many threats that novel virus infections can pose for humanity. While numerous unknowns are being investigated in terms of the distributed damage that the virus can do ...
arxiv  

Glial grafting for demyelinating disease [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2005
Remyelination of demyelinated central nervous system (CNS) axons is considered as a potential treatment for multiple sclerosis, and it has been achieved in experimental models of demyelination by transplantation of pro-myelinating cells. However, the experiments undertaken have not addressed the need for tissue-type matching in order to achieve graft ...
W. F. Blakemore, Vanja Tepavcevic
openaire   +2 more sources

The virology of demyelinating diseases [PDF]

Annals of Neurology, 1994
Infectious agents have been postulated as causes of multiple sclerosis for over a century. The possible role of a virus or viruses is supported by data that (1) a childhood exposure is involved and "viral" infections may precipitate exacerbations of disease, (2) experimental infections in animals and natural infections in humans can cause diseases with
openaire   +3 more sources

Demyelinating neuropathy as the initial presentation of familial E200K Creutzfeldt–Jakob disease in two patients

Annals of Clinical and Translational Neurology
Objective To describe peripheral neuropathy associated with familial Creutzfeldt‐Jakob disease. Methods We report two unrelated patients with genetic Creutzfeldt–Jakob disease with demyelinating peripheral neuropathy as initial presentation, with a ...
Cécile Delorme, Antoine Pégat, Julian Theuriet, Jean‐Philippe Brandel, Emmanuel Roze, Karine Viala, Julie Zyss, Stéphane Thobois, Anthony Fourier, Emilien Bernard, Juliette Svahn, Chloé Laurencin, Paul Jaulent, Christophe Vandendries, Isabelle Quadrio, Virginie Desestret, David Meyronet, Thierry Maisonobe, Stéphane Haïk, Danielle Seilhean   +19 more
doaj   +1 more source

Coexistence of Multiple Sclerosis and Brain Tumor: An Uncommon Diagnostic Challenge

Advanced Biomedical Research, 2017
Nonneoplastic demyelinating processes of the brain with mass effect on magnetic resonance imaging can cause diagnostic difficulties. It requires differential diagnosis between the tumefactive demyelinating lesion and the coexistence of neoplasm.
Fatemeh Abrishamchi, Fariborz Khorvash
doaj   +1 more source

Inflammatory demyelinating polyneuropathy versus leptomeningeal disease following Ipilimumab

Journal for ImmunoTherapy of Cancer, 2018
Background Ipilimumab is an FDA-approved anti-CTLA-4 monoclonal antibody used in treatment of metastatic melanoma. We present an unusual neurological complication of Ipilimumab therapy and the diagnostic dilemma it caused. Case presentation A 42 year old
Lorraine Cafuir, David Lawson, Nilesh Desai, Vita Kesner, Alfredo Voloschin   +4 more
doaj   +1 more source

Vision-Related Quality of Life in Patients With Atypical Optic Neuritis

Frontiers in Pain Research, 2022
AimTo evaluate the vision-related quality of life (QOL) in patients with atypical optic neuritis through the 39-item National Eye Institute Visual Function Questionnaire (NEI VFQ-39).MethodsFifty-seven patients with atypical optic neuritis were scheduled
Zhaocai Jiang, Zhaocai Jiang, Haiyan Qian, Shihui Wei   +3 more
doaj   +1 more source

The impact of gut microbiome on neuro-autoimmune demyelinating diseases

Academia Biology
Demyelinating diseases, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and chronic inflammatory demyelinating polyneuropathy (CIDP), are characterized by dysregulated immune responses to self-antigens ...
Pouria Abolfazli, Cristina Nkene Apue Nchama, Brandon Lucke-Wold   +2 more
doaj   +1 more source

A chemotaxis reaction-diffusion model for Multiple Sclerosis with Allee effect [PDF]

arXiv, 2023
In this paper, we study a modification of the mathematical model describing inflammation and demyelination patterns in the brain caused by Multiple Sclerosis proposed in [Lombardo et al. (2017), Journal of Mathematical Biology, 75, 373--417]. In particular, we hypothesize a minimal amount of macrophages to be able to start and sustain the inflammatory ...
arxiv  

Genetics of Demyelinating Diseases

Brain Pathology, 1996
Multiple sclerosis(MS), the prototypic demyelinating disease in humans, is the most common cause of acquired neurological dysfunction arising between early to mid adulthood. MS is an inflammatory disorder and is believed to result from an autoimmune response, directed against myelin proteins and perhaps other antigens, resulting in demyelination and ...
Jorge R. Oksenberg, Stephen L. Hauser, Eric Seboun   +2 more
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