Results 41 to 50 of about 12,701 (197)

Nanoporous silica-based protocells at multiple scales for designs of life and nanomedicine. [PDF]

open access: yes, 2015
Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Brinker, C Jeffrey   +3 more
core   +2 more sources

Rapid preparation of giant unilamellar vesicles. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1996
We report here a rapid evaporation method that produces in high yield giant unilamellar vesicles up to 50 microns in diameter. The vesicles are obtained after only 2 min and can be prepared from different phospholipids, including L-alpha-phosphatidylcholine (lecithin), dipalmitoleoyl L-alpha-phosphatidylcholine, and beta-arachidonoyl gamma-palmitoyl L ...
A, Moscho   +4 more
openaire   +2 more sources

Imaging of photoacoustic-mediated permeabilization of giant unilamellar vesicles (GUVs)

open access: yesScientific Reports, 2021
Target delivery of large foreign materials to cells requires transient permeabilization of the cell membrane without toxicity. Giant unilamellar vesicles (GUVs) mimic the phospholipid bilayer of the cell membrane and are also useful drug delivery ...
Diogo A. Pereira   +9 more
doaj   +1 more source

A Note on Vestigial Osmotic Pressure

open access: yesMembranes, 2023
Recent experiments have indicated that at least a part of the osmotic pressure across the giant unilamellar vesicle (GUV) membrane was balanced by the rapid formation of the monodisperse daughter vesicles inside the GUVs through an endocytosis-like ...
Hao Wu   +2 more
doaj   +1 more source

Coupling between pore formation and phase separation in charged lipid membranes [PDF]

open access: yes, 2015
We investigated the effect of charge on the membrane morphology of giant unilamellar vesicles (GUVs) composed of various mixtures containing charged lipids.
Hamada, Tsutomu   +5 more
core   +2 more sources

Membrane sculpting by curved DNA origami scaffolds

open access: yesNature Communications, 2018
BAR domain proteins feature a “banana-like” shape which is thought to aid membrane scaffolding and membrane tubulation. Here authors use DNA origami mimicking BAR domains, giant unilamellar vesicles and fluorescence imaging to study how different BAR ...
Henri G. Franquelim   +4 more
doaj   +1 more source

Formation of unilamellar dipalmitoylphosphatidylcholine vesicles promoted by Ca2+ ions: A small-angle neutron scattering study [PDF]

open access: yes, 2007
Dipalmitoylphosphatidylcholine (DPPC) was hydrated in 0.2-60 mM solution of CaCl 2 in heavy water and thoroughly homogenized by freezing-thawing process.
Almásy, László   +3 more
core   +1 more source

Mechanism of cellular uptake of genotoxic silica nanoparticles. [PDF]

open access: yes, 2012
Mechanisms for cellular uptake of nanoparticles have important implications for nanoparticulate drug delivery and toxicity. We have explored the mechanism of uptake of amorphous silica nanoparticles of 14 nm diameter, which agglomerate in culture medium ...
Brown, AP   +5 more
core   +3 more sources

Deciphering the Assembly of Enveloped Viruses Using Model Lipid Membranes

open access: yesMembranes, 2022
The cell plasma membrane is mainly composed of phospholipids, cholesterol and embedded proteins, presenting a complex interface with the environment.
Erwan Brémaud   +2 more
doaj   +1 more source

Membrane‐Penetrating Molecular Device Based on a Triplex Containing Acyclic L‐Threoninol Nucleic Acid Functionalized with Cholesterol

open access: yesAngewandte Chemie, EarlyView.
A membrane‐penetrating molecular device composed of triplex containing cholesterol‐modified acyclic L‐threoninol nucleic acid (L‐aTNA) was achieved. This device is applied to a photo‐triggered signal transduction system functioning on giant unilamellar vesicles. Abstract Membrane‐penetrating molecular devices are valuable biological tools.
Kaifu Liu   +2 more
wiley   +2 more sources

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