Results 41 to 50 of about 1,617,704 (264)

Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis.

Journal of the American Medical Association (JAMA), 2016
Importance Low-density lipoprotein cholesterol (LDL-C)-lowering alleles in or near NPC1L1 or HMGCR, encoding the respective molecular targets of ezetimibe and statins, have previously been used as proxies to study the efficacy of these lipid-lowering ...
L. Lotta, S. Sharp, S. Burgess, J. Perry, I. Stewart, Sara M. Willems, J. Luan, E. Ardanaz, L. Arrióla, B. Balkau, H. Boeing, P. Deloukas, N. Forouhi, P. Franks, S. Grioni, R. Kaaks, T. Key, C. Navarro, P. Nilsson, K. Overvad, D. Palli, S. Panico, J. Quirós, E. Riboli, O. Rolandsson, C. Sacerdote, Elena C Salamanca, N. Slimani, A. Spijkerman, A. Tjønneland, R. Tumino, D. van der A, Y. T. van der Schouw, M. McCarthy, I. Barroso, S. O’Rahilly, D. Savage, N. Sattar, C. Langenberg, R. Scott, N. Wareham   +40 more
semanticscholar   +1 more source

Effects of Diet Composition and Insulin Resistance Status on Plasma Lipid Levels in a Weight Loss Intervention in Women. [PDF]

, 2016
BackgroundOptimal macronutrient distribution of weight loss diets has not been established. The distribution of energy from carbohydrate and fat has been observed to promote differential plasma lipid responses in previous weight loss studies, and insulin
Flatt, Shirley W, Heath, Dennis D, Le, Tran, Natarajan, Loki, Pakiz, Bilge, Quintana, Elizabeth L, Rana, Brinda K, Rock, Cheryl L   +7 more
core   +3 more sources

Association of rheumatoid arthritis disease activity and antibodies to periodontal bacteria with serum lipoprotein profile in drug naive patients [PDF]

, 2020
Objective: We investigated lipid concentrations, particle sizes and antibodies binding to periodontal bacteria Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis and to malondialdehyde-acetaldehyde (MAA) modified low-density lipoprotein ...
Arstila, Leena, Elfving, Pia, Hämäläinen, Mari, Hörkkö, Sohvi, Kaipiainen-Seppänen, Oili, Kautiainen, Hannu, Kononoff, Aulikki, Laasonen, Leena, Marjoniemi, Olga, Moilanen, Eeva, Niinisalo, Helena, Pussinen, Pirkko, Rutanen, Jarno, Savolainen, Elina, Vuolteenaho, Katriina   +14 more
core   +1 more source

Atherogenic Lipoprotein Determinants of Cardiovascular Disease and Residual Risk Among Individuals With Low Low‐Density Lipoprotein Cholesterol

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background Levels of LDL (low‐density lipoprotein) cholesterol in the population are declining, and increasing attention is being focused on residual lipid‐related pathways of atherosclerotic cardiovascular disease risk beyond LDL cholesterol.
P. Lawler, A. Akinkuolie, Audrey Y. Chu, Svati H. Shah, W. Kraus, D. Craig, Latha Padmanabhan, R. Glynn, P. Ridker, D. Chasman, S. Mora   +10 more
semanticscholar   +1 more source

Relation of hyperlipidemia in serum and loss of high density lipoproteins in urine in the nephrotic syndrome [PDF]

, 1987
The mechanism leading to hyperlipidemia in the nephrotic syndrome is not fully understood but may be related in part to loss of high density lipoproteins in the urine of patients with nephrosis.
Appel, Baxter, Baxter, Chopra, De Mendoza, Eggstein, Felts, Gherardi, Gherardi, Havel, Jüngst, Jüngst, Kashyap, Klahr, Lopes-Virella, Newmark, Ohta, Röschlau, Sachs, Sata, Tamm, Wada, Weichselbaum   +22 more
core   +1 more source

High expression of antioxidant proteins in dendritic cells: possible implications in atherosclerosis [PDF]

Mol Cell Proteomics 5 (04/2006) 726-36, 2006
Dendritic cells (DCs) display the unique ability to activate naive T cells and to initiate primary T cell responses revealed in DC-T cell alloreactions. DCs frequently operate under stress conditions. Oxidative stress enhances the production of inflammatory cytokines by DCs.
arxiv   +1 more source

Serum low-density lipoprotein and low-density lipoprotein expression level at diagnosis are favorable prognostic factors in patients with small-cell lung cancer (SCLC)

BMC Cancer, 2017
BackgroundPatients with small-cell lung cancer (SCLC) patients demonstrate varied survival outcomes. Previous studies have reported that lipoproteins are associated with prognosis in various cancers; however, the role of low-density lipoprotein (LDL) and
Ting Zhou, J. Zhan, W. Fang, Yuanyuan Zhao, Yunpeng Yang, X. Hou, Zhonghan Zhang, Xiaobo He, Yaxiong Zhang, Yan Huang, Li Zhang   +10 more
semanticscholar   +1 more source

Sweet potato (Ipomoea batatas L.) leaves suppressed oxidation of low density lipoprotein (LDL) in vitro and in human subjects [PDF]

, 2011
Sweet potato (Ipomoea batatas L.) leaves are consumed as vegetables around the world, especially in Southeast Asia. The aim of this study was to investigate the inhibitory effect of sweet potato leaves on low-density lipoprotein oxidation in vitro and in
Iizuka, Maki, Ikeguchi, Motoya, Kamiya, Tomoyasu, Kishimoto, Yoshimi, Kondo, Kazuo, Nagai, Miu, Saita, Emi, Tani, Mariko, Toyozaki, Miku   +8 more
core   +2 more sources

A new lipid-structured model to investigate the opposing effects of LDL and HDL on atherosclerotic plaque macrophages [PDF]

arXiv, 2022
Atherosclerotic plaques form in artery walls due to a chronic inflammatory response driven by lipid accumulation. A key component of the inflammatory response is the interaction between monocyte-derived macrophages and extracellular lipid. Although concentrations of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles in the blood
arxiv  

Lipids and Lipoproteins in Health and Disease: Focus on Targeting Atherosclerosis

Biomedicines, 2021
Despite advances in pharmacotherapy, intervention devices and techniques, residual cardiovascular risks still cause a large burden on public health. Whilst most guidelines encourage achieving target levels of specific lipids and lipoproteins to reduce ...
Chih-Kuo Lee, Che-Wei Liao, Shih-Wei Meng, Wei-Kai Wu, Jiun-Yang Chiang, Ming-Shiang Wu   +5 more
doaj   +1 more source