Results 41 to 50 of about 617,302 (345)

The role of MEOX1 in non-neoplastic and neoplastic diseases

open access: yesBiomedicine & Pharmacotherapy, 2023
Targeted gene therapy has shown durable efficacy in non-neoplastic and neoplastic patients. Therefore, finding a suitable target has become a key area of research. Mesenchyme homeobox 1 (MEOX1) is a transcriptional factor that plays a significant role in regulation of somite development.
Guoqiang Zeng   +7 more
openaire   +2 more sources

The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells.

open access: yesBlood, 1985
Ki-1 is a monoclonal antibody (raised against a Hodgkin's disease-derived cell line) that, in biopsy tissue affected by Hodgkin's disease, reacts selectively with Reed-Sternberg cells.
H. Stein   +11 more
semanticscholar   +1 more source

Breast MRI in Pregnancy-Associated Breast Cancer

open access: yes대한영상의학회지, 2017
Purpose The purpose of this study was to evaluate the usefulness of MR imaging and to describe the MR imaging findings of pregnancy-associated breast cancer. Materials and Methods From 2006 to 2013, MR images of 23 patients with pregnancy-associated
Shin Jung Kim   +7 more
doaj   +1 more source

Agreement and differentiation of intradural spinal cord lesions in dogs using magnetic resonance imaging

open access: yesJournal of Veterinary Internal Medicine, 2022
Background Magnetic resonance imaging is the method of choice for diagnosing spinal cord neoplasia, but the accuracy of designating the relationship of a neoplasm to the meninges and agreement among observers is unknown. Objectives To determine agreement
Maya S. Krasnow   +10 more
doaj   +1 more source

Microenvironmental Signals and Biochemical Information Processing: Cooperative Determinants of Intratumoral Plasticity and Heterogeneity

open access: yesFrontiers in Cell and Developmental Biology, 2018
Intra-tumor cellular heterogeneity is a major challenge in cancer therapy. Tumors are composed of multiple phenotypic subpopulations that vary in their ability to initiate metastatic tumors and in their sensitivity to chemotherapy.
Alexander E. Davies, John G. Albeck
doaj   +1 more source

IMMUNOHISTOCHEMICAL EXPRESSION OF STEM CELL MARKERS CD44, CD166 AND ALDH1A1 IN NON-NEOPLASTIC POLYPS OF THE COLON IN SAMPLE OF IRAQI PATIENTS [PDF]

open access: yesBasrah Journal of Surgery, 2017
IMMUNOHISTOCHEMICAL EXPRESSION OF STEM CELL MARKERS CD44, CD166 AND ALDH1A1 IN NON-NEOPLASTIC POLYPS OF THE COLON IN SAMPLE OF IRAQI PATIENTS Nawal M Abdullah*, Mustafa M Ibraheem@ & Basim Sh Ahmed# *MB,ChB, MSc, Assist. Prof., Department of Anatomy,
Basim Sh Ahmed   +2 more
doaj   +1 more source

Neoplastic Leg Ulcers

open access: yesDermatopathology, 2018
Skin biopsy is an important procedure for a correct diagnosis of varying skin conditions, from inflammatory to neoplastic diseases. Nevertheless, some authors still consider this procedure a high risk in patients affected by leg ulcers (LUs) and prefer reserving it for selected cases [1].
Sacchelli, Lidia   +5 more
openaire   +4 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Mesenchymal Stem Cells, Bioactive Factors, and Scaffolds in Bone Repair: From Research Perspectives to Clinical Practice

open access: yesCells, 2021
Mesenchymal stem cell-based therapies are promising tools for bone tissue regeneration. However, tracking cells and maintaining them in the site of injury is difficult. A potential solution is to seed the cells onto a biocompatible scaffold.
Sandra Stamnitz, Aleksandra Klimczak
doaj   +1 more source

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