Results 41 to 50 of about 211,100 (336)

Antinociceptive activity of the S1P-receptor agonist FTY720 [PDF]

, 2008
FTY720 is a novel immunosuppressive drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. In its phosphorylated form FTY720 is a potent S1P receptor agonist.
Angioni, Carlo Federico, Brenneis, Christian, Coste, Ovidiu, Geisslinger, Gerd, Marian, Claudiu, Pierre, Sandra, Popp, Laura, Schmidt, Helmut, Scholich, Klaus   +8 more
core   +1 more source

Inflamm-aging and arachadonic acid metabolite differences with stage of tendon disease. [PDF]

PLoS ONE, 2012
The contribution of inflammation to the pathogenesis of tendinopathy and high prevalence of re-injury is not well established, although recent evidence suggests involvement of prostaglandins.
Stephanie Georgina Dakin, Jayesh Dudhia, Natalie Jayne Werling, Dirk Werling, Dilkush Robert Ephrem Abayasekara, Roger Kenneth Whealands Smith   +5 more
doaj   +1 more source

Attenuation of ischemic liver injury by prostaglandin E1 analogue, misoprostol, and prostaglandin I2 analogue, OP-41483 [PDF]

, 1998
Background: Prostaglandin has been reported to have protective effects against liver injury. Use of this agent in clinical settings, however, is limited because of drugrelated side effects.
Ishizaki, N, Jin, MB, Kawashima, Y, Shimamura, T, Starzl, TE, Todo, S, Totsuka, E, Urakami, A, Zhu, Y   +8 more
core   +1 more source

A Blend of F Prostaglandins Functions as an Attractive Sex Pheromone in Silver Carp

Fishes, 2019
A series of laboratory experiments tested the hypothesis that the Silver Carp (Hypophthalmichthys molitrix), an invasive river carp from China, employs a prostaglandin F2α-derived sex pheromone that is attractive and species-specific.
Peter W. Sorensen, Mara C. P. Rue, Joseph M. Leese, Ratna Ghosal, Hangkyo Lim   +4 more
doaj   +1 more source

Effect of ultrasonic modification on the protective activity of Flammulina velutipes polysaccharide to prevent ethanol-induced injury on GES-1 cells

Food Science and Human Wellness, 2023
Flammulina velutipes (F. velutipes) polysaccharides were modified by ultrasound at the rated power of 150 W and 900 W. The monosaccharide composition, ultraviolet-visible, and Fourier transform infrared spectral characteristics of F.
Jinrong Xiao, Xin Chen, Jingsi Zhang, Yifan Wang, Lei Zhong, Qiping Zhan, Qiuhui Hu, Liyan Zhao   +7 more
doaj   +1 more source

Effect of oleic acid supplementation on prostaglandin production in maternal endometrial and fetal allantochorion cells isolated from late gestation ewes [PDF]

, 2015
Elevated circulating non-esterified fatty acids including oleic acid (OA) are associated with many pregnancy related complications. Prostaglandins (PGs) play crucial roles during parturition.
Aardema, Alves, Arsic, Asselin, Carluccio, Catov, Challis, Chen, Cheng, Cheng, Cheng, Cheng, Cherny, Chu, Crane, D.C. Wathes, D.R.E. Abayasekara, Flynn, Goncalves, Guillou, Herath, Jabbour, Karsch, Kim, Klein, Lamont, Lee, Leung, Lewis, Lunn, M. Elmes, Nielsen, Noble, Poyser, Reddy, Rimoldi, Robinson, S. Kirkup, Sharp, Smith, Smith, Thorburn, Villa, Wang, Wathes, Wendell, Whittle, Witkin, Z. Cheng, Zhang   +49 more
core   +2 more sources

A Coculture Model of Intrahepatic Islet Transplantation: Activation of Kupffer Cells by Islets and Acinar Tissue

Cell Transplantation, 2001
Clinical and experimental studies of intrahepatic islet transplantation have allowed histological and systemic observations to be made, but the location of the transplanted islets makes it difficult to assess direct effects on the cells of the liver.
Heather A. Clayton, Joanna E. Davies, Chris D. Sutton, Peter R. F. Bell, Ashley R. Dennison   +4 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Prostaglandins and its analogues : An approach for treatment of anoestrus and to enhance breeding efficiency [PDF]

Veterinary World, 2012
Cloprostenol is a synthetic prostaglandin F analogue. It is a FP (Prostaglandin F) receptor agonist, which shows 2á powerful luteolytic effects.
G B Dudhatra, S K Mody, H B Patel, C M Modi, A B Chukewar, Avinash Kumar, M M Awale   +6 more
doaj  

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source