Results 41 to 50 of about 194,880 (152)

Expression quantitative trait loci analysis in plants [PDF]

, 2010
An expression Quantitative Trait Locus or eQTL is a chromosomal region that accounts for a proportion of the variation in abundance of a mRNA transcript observed between individuals in a genetic mapping population.
Chen, Xinwei, Druka, Arnis, Jiang, Ning, Kearsey, Mike, Luo, Zewei, Potokina, Elena, Waugh, Robbie   +6 more
core   +2 more sources

Rare variants contribute disproportionately to quantitative trait variation in yeast. [PDF]

, 2019
How variants with different frequencies contribute to trait variation is a central question in genetics. We use a unique model system to disentangle the contributions of common and rare variants to quantitative traits.
Bloom, Joshua S, Boocock, James, Day, Laura, Kruglyak, Leonid, Oates-Barker, Holly, Sadhu, Meru J, Treusch, Sebastian   +6 more
core   +1 more source

Quantitative trait loci for bone traits segregating independently of those for growth in an F-2 broiler X layer cross [PDF]

, 2007
An F broiler-layer cross was phenotyped for 18 skeletal traits at 6, 7 and 9 weeks of age and genotyped with 120 microsatellite markers. Interval mapping identified 61 suggestive and significant QTL on 16 of the 25 linkage groups for 16 traits.
A.S. Law, Bradshaw RH, D.R. Morrice, D.W. Burt, de Koning DJ, de Koning DJ, Duff SRI, Haley CS, Hiney KM, Hocking PM, Hocking PM, Ikeobi CON, Ikeobi CON, Jansen R, Knott SA, Law AS, Manichaikul A, Moore T, Navarro P, Nicholson D, P.M. Hocking, P.W.A. Sharman, Sasaki O, Schreiweis MA, Seaton G, Sewalem A, Smith C, Williams B, Wong GKS, Zeng Z-B   +29 more
core   +1 more source

Population differences in transcript-regulator expression quantitative trait loci.

PLoS ONE, 2012
Gene expression quantitative trait loci (eQTL) are useful for identifying single nucleotide polymorphisms (SNPs) associated with diseases. At times, a genetic variant may be associated with a master regulator involved in the manifestation of a disease ...
Pierre R Bushel, Ray McGovern, Liwen Liu, Oliver Hofmann, Ahsan Huda, Jun Lu, Winston Hide, Xihong Lin   +7 more
doaj   +1 more source

Identification of potential therapeutic targets for problematic alcohol use using multi-omics dataResearch in context

EBioMedicine
Summary: Background: Problematic alcohol use (PAU) is a serious global health issue with limited treatment options. Although genetic studies have identified genomic regions associated with PAU, the specific causal genes and proteins remain unclear. This
Dong June Lee, Minku Song, Soohyun Lim, Sanghyeon Park, Hyejin Kim, Yeeun Ahn, Faith Choi, Woojae Myung, Hong-Hee Won   +8 more
doaj   +1 more source

Fourteen years of R/qtl: Just barely sustainable

, 2014
R/qtl is an R package for mapping quantitative trait loci (genetic loci that contribute to variation in quantitative traits) in experimental crosses. Its development began in 2000. There have been 38 software releases since 2001.
Broman, Karl W.
core   +2 more sources

Development of a Next-Generation NIL Library in Arabidopsis Thaliana for Dissecting Complex Traits [PDF]

, 2013
The identification of the loci and specific alleles underlying variation in quantitative traits is an important goal for evolutionary biologists and breeders.
Bauerle, William L., Fletcher, Richard S., Juenger, Thomas E., McKay, John K., Meyer, Eli, Mullen, Jack L., Reuning, Gretchen, Sen, Saunak, Yoder, Seth   +8 more
core   +3 more sources

Loci nominally associated with autism from genome-wide analysis show enrichment of brain expression quantitative trait loci but not lymphoblastoid cell line expression quantitative trait loci

Molecular Autism, 2012
Background Autism spectrum disorder is a severe early onset neurodevelopmental disorder with high heritability but significant heterogeneity. Traditional genome-wide approaches to test for an association of common variants with autism susceptibility risk
Davis Lea K, Gamazon Eric R, Kistner-Griffin Emily, Badner Judith A, Liu Chunyu, Cook Edwin H, Sutcliffe James S, Cox Nancy J   +7 more
doaj   +1 more source

Identification of Quantitative Trait Loci Determining Vegetative Growth Traits in Coffea Canephor [PDF]

, 2011
Recently the use of molecular markers has been successfully applied for some crops. For coffee, new opportunities have been opened since Nestlé R&D Centre in collaboration with ICCRI completed the first genetic map of Coffea canephora. This study was
Crouzillat, C. (Crouzillat), Priyono, P. (Priyono), Sumirat, U. (Ucu)   +2 more
core  

Mapping QTLs for mineral accumulation and shoot dry biomass under different Zn nutritional conditions in Chinese cabbage ( Brassica rapa L. ssp. pekinensis ) [PDF]

, 2008
Chinese cabbage (Brassica rapa L. ssp. pekinensis) is one of the most important vegetables in China. Genetic dissection of leaf mineral accumulation and tolerance to Zn stress is important for the improvement of the nutritional quality of Chinese cabbage
Aarts, M.G.M., Koornneef, M., Li, X., Li, Y., Song, X., Sun, R., Wang, X.W., Wu, J., Yuan, Y.X., Zhang, X.W., Zhao, J.   +10 more
core   +2 more sources