Results 41 to 50 of about 56,983 (273)
Checkpoint Inhibitor-Associated Scleroderma and Scleroderma Mimics
Immune checkpoint inhibitors (ICI) are the standard of care for various malignancies and have been associated with a wide spectrum of complications that are phenotypically akin to primary autoimmune diseases.
Michael Macklin+3 more
doaj +1 more source
Synchrotron-based near-field photothermal microspectroscopy: Development of a quantitative nanohistology set-up with expansion of the infrared capability 2 [PDF]
The purpose was two-fold: To explore the capability of the Diamond Synchrotron infra-red so as to include near-field photothermal microspectroscopy (PTMS); and Toward a quantitative nanohistology - investigation of scleroderma using synchrotron radiation (mu- FTIR). With recent advances in AFM, the integration of an IR temperature-based system on an IR
arxiv
In this study we define long‐term characteristics of various neurological autoimmune disorders encountered after SARS‐CoV‐2 vaccinations. Long‐term outcome was favorable in most cases. Re‐vaccinations were well‐tolerated and should be considered on an individual risk/benefit analysis.
Sofia Doubrovinskaia+11 more
wiley +1 more source
Immunoregulatory Role of HLA-G in Allergic Diseases
Allergic diseases are sustained by a T-helper 2 polarization leading to interleukin-4 secretion, IgE-dependent inflammation, and mast cell and eosinophil activation.
Giuseppe Murdaca+4 more
doaj +1 more source
Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma
Scleroderma is a multiorgan connective tissue disease characterized by autoantibody production and fibroproliferative stenosis of the microvasculature. The development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in patients with ...
B N Shiva Prasad, H A Karthik Urala
doaj +1 more source
Causal Inference using Multivariate Generalized Linear Mixed-Effects Models with Longitudinal Data [PDF]
Dynamic prediction of causal effects under different treatment regimes conditional on an individual's characteristics and longitudinal history is an essential problem in precision medicine. This is challenging in practice because outcomes and treatment assignment mechanisms are unknown in observational studies, an individual's treatment efficacy is a ...
arxiv
A 72-year-old man with diabetes-associated scleredema is presented. The patient had a long history of diabetes mellitus that had been difficult to control with complications of retinopathy, nephropathy, and arteriosclerosis leading to myocardial infarcts and stroke.
openaire +3 more sources
Autoantibodies and scleroderma phenotype define subgroups at high-risk and low-risk for cancer
Objectives Recent studies demonstrate autoantibodies are powerful tools to interrogate molecular events linking cancer and the development of autoimmunity in scleroderma.
T. Igusa+7 more
semanticscholar +1 more source
Cyclophosphamide versus placebo in scleroderma lung disease.
BACKGROUND We conducted a double-blind, randomized, placebo-controlled trial to determine the effects of oral cyclophosphamide on lung function and health-related symptoms in patients with evidence of active alveolitis and scleroderma-related ...
D. Tashkin+30 more
semanticscholar +1 more source
Systemic sclerosis is considered a disease dominated by a “loss of angiogenesis”, although in its early phases evidence indicates a disturbed angiogenic response only.
Marco Matucci-Cerinic+7 more
doaj +1 more source