Results 41 to 50 of about 56,983 (273)

Checkpoint Inhibitor-Associated Scleroderma and Scleroderma Mimics

open access: yesPharmaceuticals, 2023
Immune checkpoint inhibitors (ICI) are the standard of care for various malignancies and have been associated with a wide spectrum of complications that are phenotypically akin to primary autoimmune diseases.
Michael Macklin   +3 more
doaj   +1 more source

Synchrotron-based near-field photothermal microspectroscopy: Development of a quantitative nanohistology set-up with expansion of the infrared capability 2 [PDF]

open access: yesarXiv, 2022
The purpose was two-fold: To explore the capability of the Diamond Synchrotron infra-red so as to include near-field photothermal microspectroscopy (PTMS); and Toward a quantitative nanohistology - investigation of scleroderma using synchrotron radiation (mu- FTIR). With recent advances in AFM, the integration of an IR temperature-based system on an IR
arxiv  

Neurological autoimmune diseases following vaccinations against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2): A follow‐up study

open access: yesEuropean Journal of Neurology, Volume 30, Issue 2, Page 463-473, February 2023., 2023
In this study we define long‐term characteristics of various neurological autoimmune disorders encountered after SARS‐CoV‐2 vaccinations. Long‐term outcome was favorable in most cases. Re‐vaccinations were well‐tolerated and should be considered on an individual risk/benefit analysis.
Sofia Doubrovinskaia   +11 more
wiley   +1 more source

Immunoregulatory Role of HLA-G in Allergic Diseases

open access: yesJournal of Immunology Research, 2016
Allergic diseases are sustained by a T-helper 2 polarization leading to interleukin-4 secretion, IgE-dependent inflammation, and mast cell and eosinophil activation.
Giuseppe Murdaca   +4 more
doaj   +1 more source

Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma

open access: yesIndian Journal of Rheumatology, 2021
Scleroderma is a multiorgan connective tissue disease characterized by autoantibody production and fibroproliferative stenosis of the microvasculature. The development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in patients with ...
B N Shiva Prasad, H A Karthik Urala
doaj   +1 more source

Causal Inference using Multivariate Generalized Linear Mixed-Effects Models with Longitudinal Data [PDF]

open access: yesarXiv, 2023
Dynamic prediction of causal effects under different treatment regimes conditional on an individual's characteristics and longitudinal history is an essential problem in precision medicine. This is challenging in practice because outcomes and treatment assignment mechanisms are unknown in observational studies, an individual's treatment efficacy is a ...
arxiv  

Scleroderma

open access: yesDermatology Online Journal, 2003
A 72-year-old man with diabetes-associated scleredema is presented. The patient had a long history of diabetes mellitus that had been difficult to control with complications of retinopathy, nephropathy, and arteriosclerosis leading to myocardial infarcts and stroke.
openaire   +3 more sources

Autoantibodies and scleroderma phenotype define subgroups at high-risk and low-risk for cancer

open access: yesAnnals of the Rheumatic Diseases, 2018
Objectives Recent studies demonstrate autoantibodies are powerful tools to interrogate molecular events linking cancer and the development of autoimmunity in scleroderma.
T. Igusa   +7 more
semanticscholar   +1 more source

Cyclophosphamide versus placebo in scleroderma lung disease.

open access: yesNew England Journal of Medicine, 2006
BACKGROUND We conducted a double-blind, randomized, placebo-controlled trial to determine the effects of oral cyclophosphamide on lung function and health-related symptoms in patients with evidence of active alveolitis and scleroderma-related ...
D. Tashkin   +30 more
semanticscholar   +1 more source

The “myth” of loss of angiogenesis in systemic sclerosis: a pivotal early pathogenetic process or just a late unavoidable event?

open access: yesArthritis Research & Therapy, 2017
Systemic sclerosis is considered a disease dominated by a “loss of angiogenesis”, although in its early phases evidence indicates a disturbed angiogenic response only.
Marco Matucci-Cerinic   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy