Results 1 to 10 of about 165,902 (383)

Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase.

open access: yesPLoS ONE, 2019
Cordycepin is an efficient component of Cordyceps spp, a traditional Chinese medicine widely used for healthcare in China, and has been recently acted as a strong anticancer agent for clinic.
Feng Huang   +4 more
doaj   +1 more source

On the parabolic-elliptic Keller-Segel system with signal-dependent motilities: a paradigm for global boundedness and steady states [PDF]

open access: yes, 2020
This paper is concerned with a parabolic-elliptic Keller-Segel system where both diffusive and chemotactic coefficients (motility functions) depend on the chemical signal density. This system was originally proposed by Keller and Segel in \cite{KS-1971-JTB2} to describe the aggregation phase of {\it Dictyostelium discoideum} cells in response to the ...
arxiv   +1 more source

A Critical-like Collective State Leads to Long-range Cell Communication in Dictyostelium discoideum Aggregation [PDF]

open access: yesFinal version (mainly different Fig. 4 and a bit less technical): De Palo G, Yi D, Endres RG. PLoS Biol. 15(4): e1002602 (2017), 2018
The transition from single-cell to multicellular behavior is important in early development but rarely studied. The starvation-induced aggregation of the social amoeba Dictyostelium discoideum into a multicellular slug is known to result from single-cell chemotaxis towards emitted pulses of cyclic adenosine monophosphate (cAMP). However, how exactly do
arxiv   +1 more source

Bradykinin postconditioning protects rat hippocampal neurons after restoration of spontaneous circulation following cardiac arrest via activation of the AMPK/mTOR signaling pathway

open access: yesNeural Regeneration Research, 2022
Bradykinin (BK) is an active component of the kallikrein-kinin system that has been shown to have cardioprotective and neuroprotective effects. We previously showed that BK postconditioning strongly protects rat hippocampal neurons upon restoration of ...
Shi-Rong Lin   +7 more
doaj   +1 more source

Phosphorus availability regulates intracellular nucleotides in marine eukaryotic phytoplankton

open access: yesLimnology and Oceanography Letters, 2017
Marine eukaryotic phytoplankton adapt to low phosphorus (P) in the oceans through a variety of step‐wise mechanisms including lipid substitution and decreased nucleic acid content.
Elizabeth B. Kujawinski   +6 more
doaj   +1 more source

Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells

open access: yeseLife, 2014
Apoptosis is coupled with recruitment of macrophages for engulfment of dead cells, and with compensatory proliferation of neighboring cells. Yet, this death process is silent, and it does not cause inflammation.
Hiroshi Yamaguchi   +3 more
doaj   +1 more source

Mechanobiology predicts raft formations triggered by ligand-receptor activity across the cell membrane [PDF]

open access: yes, 2020
Clustering of ligand-binding receptors of different types on thickened isles of the cell membrane, namely lipid rafts, is an experimentally observed phenomenon. Although its influence on cell response is deeply investigated, the role of the coupling between mechanical processes and multiphysics involving the active receptors and the surrounding lipid ...
arxiv   +1 more source

The effect of red ginseng and ginseng leaves on the substance and energy metabolism in hypothyroidism rats

open access: yesJournal of Ginseng Research, 2017
Background: Recent studies have revealed that the properties Traditional Chinese Medicine is mostly associated with are substance and energy metabolism.
Hang Xiao   +3 more
doaj   +1 more source

Histamine levels following adenosine monophosphate challenge [PDF]

open access: yesRespiratory Medicine, 2005
n ...
E. Bucchioni   +8 more
openaire   +3 more sources

Antidepressant effect of electroacupuncture regulates signal targeting in the brain and increases brain-derived neurotrophic factor levels

open access: yesNeural Regeneration Research, 2016
Electroacupuncture improves depressive behavior faster and with fewer adverse effects than antidepressant medication. However, the antidepressant mechanism of electroacupuncture remains poorly understood.
Dong-mei Duan   +3 more
doaj   +1 more source

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