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Angiotensin-Converting Enzyme Inhibitors [PDF]
The Journal of Clinical Hypertension, 2011 KEY POINTS AND RECOMMENDATIONS: • In addition to hypertension, angiotensin-converting enzyme inhibitors are indicated for treatment of patients at high risk for coronary artery disease, after myocardial infarction, with dilated cardiomypathy, or with chronic kidney disease.
Joseph L. Izzo, Matthew R. Weir
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Angiotensin-Converting Enzyme Inhibitors [PDF]
Circulation, 1998 Abstract —ACE inhibitors have achieved widespread usage in the treatment of cardiovascular and renal disease. ACE inhibitors alter the balance between the vasoconstrictive, salt-retentive, and hypertrophic properties of angiotensin II (Ang II) and the vasodilatory and natriuretic properties of bradykinin and alter the ...
Douglas E. Vaughan, Nancy J. Brown
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, 2021 Angiotensin converting enzyme (ACE) is well known for its dual actions to convert inactive Ang I to active Ang II, and degrades active bradykinin (BK), which plays an important role in controlling blood pressure. Because it is the bottleneck step for the production of pressor Ang II, it was targeted pharmacologically in the 1970s.
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Signaling by the Angiotensin-Converting Enzyme [PDF]
Circulation Research, 2006 Inhibition of the angiotensin-converting enzyme (ACE) protects against the progression of several cardiovascular diseases. Because of its dual role in regulating angiotensin II and bradykinin levels, the positive clinical effects of ACE inhibitors were thought to be the consequence of concomitant reductions in the production of angiotensin II and the ...
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Angiotensin-converting enzyme and male fertility [PDF]
Proceedings of the National Academy of Sciences, 1998 The angiotensin-converting enzyme (ACE; EC3.4.15.1) gene (Ace) encodes both a somatic isozyme found in blood and several other tissues, including the epididymis, and a testis-specific isozyme (testis ACE) found only in developing spermatids and mature sperm.
Oliver Smithies +8 more
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Angiotensin-Converting Enzyme Inhibitors and Angioedema [PDF]
Allergy, Asthma and Immunology Research, 2010 To investigate the incidence and clinical characteristics of angioedema associated with the use of angiotensin-converting enzyme inhibitors (ACEIs) in an outpatient allergy department.A retrospective review of medical records of new patients seen in an allergy clinic.
Luis González-Aveledo +1 more
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SOMATIC ANGIOTENSIN CONVERTING ENZYME IN VARICOCELE
Archives of Andrology, 2006 The ACE is found as two isozymes in the body. A somatic isozyme found in blood and several other tissues, and a testis-specific isozyme found only in developing spermatids and mature sperm. In this study, we investigated the ACE activity in left spermatic vein blood samples of infertile patients with varicocele and its correlation to spermatologic ...
Saban Sarikaya +4 more
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Serum angiotensin converting enzyme [PDF]
Thorax, 1999 Marshall and Shaw in their editorial1 are correct to hypothesise that the normal range of serum angiotensin converting enzyme (SACE) would be narrower if ACE genotype (insertion/deletion; ID) is also taken into account. This would split its wide normal range into three narrower ranges defined by the genotypes II, ID and …
P. Sharma +3 more
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Angiotensin-Converting Enzyme and Vascular Remodeling [PDF]
Circulation Research, 2007 Vascular remodeling is the result of a close interplay of changes in vascular tone and structure. In this review, the role of angiotension-converting enzyme (ACE) and the impact of ACE inhibition on vascular remodeling processes during vascular injury and restenosis, hypertension, atherosclerosis, and aneurysm formation are discussed.
Judith C. Sluimer +2 more
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Angiotensin Converting Enzymes
, 2016 Angiotensin converting enzyme (ACE) is well known for its dual actions in converting inactive Ang I to active Ang II and degrade active bradykinin (BK), which play an important role in the control of blood pressure. Since the bottle neck step is the production of pressor Ang II, this was targeted pharmacologically in 1970s and successful ACE inhibitors
openaire +1 more source