Results 1 to 10 of about 4,479,187 (352)

Assessment of global health risk of antibiotic resistance genes

Nature Communications, 2022
Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in the last decade. Many genes can confer resistance, but evaluating the relative health risks of ARGs is complex. Factors such as the abundance, propensity for lateral
Zhenyan Zhang, Qi Zhang, Tingzhang Wang, Nuohan Xu, Tao Lu, Wenjie Hong, J. Penuelas, M. Gillings, Meixia Wang, Wenwen Gao, H. Qian   +10 more
semanticscholar   +1 more source

Discovery of a novel integron-borne aminoglycoside resistance gene present in clinical pathogens by screening environmental bacterial communities

Microbiome, 2020
Background New antibiotic resistance determinants are generally discovered too late, long after they have irreversibly emerged in pathogens and spread widely.
Maria-Elisabeth Böhm, Mohammad Razavi, Nachiket P. Marathe, Carl-Fredrik Flach, D. G. Joakim Larsson   +4 more
doaj   +1 more source

Bacterial Antibiotic Resistance: The Most Critical Pathogens

Pathogens, 2023
Antibiotics primarily act on bacterial growth by eliminating bacteria or preventing them from reproducing and spreading [...].
C. Biondo
semanticscholar   +1 more source

Antibiotic resistance: The challenges and some emerging strategies for tackling a global menace

Journal of clinical laboratory analysis (Print), 2022
Antibiotic resistance is currently the most serious global threat to the effective treatment of bacterial infections. Antibiotic resistance has been established to adversely affect both clinical and therapeutic outcomes, with consequences ranging from ...
David Chinemerem Nwobodo, M. Ugwu, Clement Oliseloke Anie, M. T. Al-Ouqaili, Joseph Chinedu Ikem, Uchenna Victor Chigozie, M. Saki   +6 more
semanticscholar   +1 more source

Quaternary ammonium disinfectants and antiseptics: tolerance, resistance and potential impact on antibiotic resistance

Antimicrobial Resistance and Infection Control, 2023
Background Due to the substantial increase in the use of disinfectants containing quaternary ammonion compounds (QACs) in healthcare and community settings during the COVID-19 pandemic, there is increased concern that heavy use might cause bacteria to ...
J. Boyce
semanticscholar   +1 more source

Bacterial Antibiotic Resistance: The Most Critical Pathogens

Pathogens, 2021
Antibiotics have made it possible to treat bacterial infections such as meningitis and bacteraemia that, prior to their introduction, were untreatable and consequently fatal.
G. Mancuso, A. Midiri, E. Gerace, C. Biondo   +3 more
semanticscholar   +1 more source

A Novel, Integron-Regulated, Class C β-Lactamase

Antibiotics, 2020
AmpC-type β-lactamases severely impair treatment of many bacterial infections, due to their broad spectrum (they hydrolyze virtually all β-lactams, except fourth-generation cephalosporins and carbapenems) and the increasing incidence of plasmid-
Maria-Elisabeth Böhm, Mohammad Razavi, Carl-Fredrik Flach, D. G. Joakim Larsson   +3 more
doaj   +1 more source

Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues [PDF]

, 2000
The veterinary use of antimicrobial drugs in food producing animals may result in residues in food, that might modify the consumer gut flora. This review compares three model systems that maintain a complex flora of human origin: (i) human flora ...
Cemiglia CE, Corpet DE, Corpet DE Antibiotic residues and drug resistance in human intestinal flora, Corpet DE Antibiotic resistance from food, Corpet DE Current status of models for testing antibiotic residues, Freter R, Licht TR, Rollins LD, Tancrede C, Vollaard El   +9 more
core   +2 more sources

Antibiotic Resistance: One Health One World Outlook

Frontiers in Cellular and Infection Microbiology, 2021
Antibiotic resistance (ABR) is a growing public health concern worldwide, and it is now regarded as a critical One Health issue. One Health’s interconnected domains contribute to the emergence, evolution, and spread of antibiotic-resistant microorganisms
B. Aslam, M. Khurshid, M. Arshad, S. Muzammil, Maria Rasool, N. Yasmeen, Taif Shah, Tamoor Hamid Chaudhry, M. Rasool, Aqsa Shahid, X. Xia, Z. Baloch   +11 more
semanticscholar   +1 more source

The Association between Insertion Sequences and Antibiotic Resistance Genes

mSphere, 2020
Insertion sequences (ISs) are abundant mobile genetic elements on bacterial genomes, responsible for mobilization of many genes, including antibiotic resistance genes (ARGs).
Mohammad Razavi, Erik Kristiansson, Carl-Fredrik Flach, D. G. Joakim Larsson   +3 more
doaj   +1 more source