Results 31 to 40 of about 2,871 (258)

Controle de força de uma prótese mioelétrica de mão com realimentação sensorial [PDF]

, 2019
Hand myoelectric prostheses that use sensory feedback can provide improvement in fragile objects manipulation and in user’s acceptance. The force sensory feedback can be done in many ways.
Furlan, Paula Brandão
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Sensory Feedback and the Dynamic Control of Movement

Annual Review of Neuroscience
Motor systems in animals are highly dependent on sensory information for optimal control and precision, with mechanosensory feedback from the somatosensory system playing a critical role. These mechanosensory pathways are woven into the descending feedforward pathways and local central pattern generator circuits that control and generate movement ...
Martyn, Goulding, Tejapratap, Bollu, Ansgar, Büschges   +2 more
openaire   +2 more sources

Neuromorphic model for transcutaneous stimulation and optimization of sensory perception levels [PDF]

, 2021
It is estimated that in Brazil about 16,064 people have suffered some kind of amputation or disarticulation of the upper limb in the last 10 years.
Costa, Ana Clara Pereira Resende da
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Sistema de resposta sensorial per una pròtesi de braç [PDF]

Aquest projecte presenta el desenvolupament d’un sistema de resposta sensorial no invasiva, basat en estímuls vibratoris i mecano-tàctils, per millorar la funcionalitat i usabilitat de les pròtesis de braç.
Puig Prujà, Jordi
core   +2 more sources

Assistive locomotion device with haptic feedback for guiding visually impaired people [PDF]

, 2020
Robotic assistive devices are able to enhance physical stability and balance. Smart walkers, in particular, are also capable of offering cognitive support for individuals whom conventional walkers are unsuitable.
Bastos, Teodiano, Frizera Neto, Anselmo, Mello, Ricardo, Jiménez Hernández, Mario Fernando   +3 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

A distributed virtual reality system for spatial updating : concepts, implementation, and experiments [PDF]

, 2000
von der Heyde M. A distributed virtual reality system for spatial updating : concepts, implementation, and experiments. Bielefeld (Germany): Bielefeld University; 2000.Introduction: Over the course of evolution humans as well as other animals learned to ...
von der Heyde, Markus, von der Heyde, M.
core   +1 more source