Results 51 to 60 of about 488,887 (308)

From thorium phosphate hydrogenphosphate hydrate to $\beta$-thorium phosphate diphosphate: Structural evolution to a radwaste storage ceramic

, 2006
$\beta$-Thorium phosphate diphosphate ($\beta$-TPD), considered as a very promising radwaste storage material, was obtained from thorium phosphate hydrogenphosphate hydrate (TPHPH) precursor through dehydration and hydrogen phosphate condensation.
Clavier, Nicolas, Wallez, G., Quarton, M., Nicolas Dacheux, Wouter van Beek, Gilles Wallez, Dacheux, N., van Beek, W., Nicolas Clavier, Michel Quarton   +9 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Synthesis and targeting of gold-coated 177Lu-containing lanthanide phosphate nanoparticles—A potential theranostic agent for pulmonary metastatic disease

APL Bioengineering, 2018
Targeted radiotherapies maximize cytotoxicity to cancer cells. In this work, we describe the synthesis, characterization, and biodistribution of antibody conjugated gold-coated lanthanide phosphate nanoparticles containing 177Lu.
Nicholas Sobol, Logan Sutherlin, Edyta Cedrowska, Joshua Schorp, Cristina Rodríguez-Rodríguez, Vesna Sossi, Jimmy Lattimer, Douglas C Miller, Paul Pevsner, J. David Robertson   +9 more
doaj   +1 more source

Exome sequencing for mucolipidosis III: Detection of a novel GNPTAB gene mutation in a patient with a very mild phenotype

Molecular Genetics and Metabolism Reports, 2015
Mucolipidosis II and III alpha/beta (ML II/III alpha/beta) are rare autosomal recessive lysosomal storage diseases that are caused by a deficiency of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase, the enzyme responsible for the ...
F. Sperb-Ludwig, T. Alegra, R.V. Velho, N. Ludwig, C.A. Kim, F. Kok, J.P. Kitajima, E. van Meel, S. Kornfeld, M.G. Burin, I.V.D. Schwartz   +10 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Conformational cycling in beta-phosphoglucomutase catalysis: Reorientation of the beta-D-glucose 1,6-(bis) phosphate intermediate

, 2006
Activated Lactococcus lactis beta-phosphoglucomutase (beta PGM) catalyzes the conversion of beta-D-glucose 1-phosphate (beta G1P) derived from maltose to beta-D-glucose 6-phosphate (G6P). Activation requires Mg2+ binding and phosphorylation of the active
Rådström, Peter, Dai, JY, Dunaway-Mariano, D, Wang, LB, Allen, KN   +4 more
core   +1 more source

Evaluation of recombinant human interferon beta 1b by liquid chromatography methods and bioassay

Brazilian Journal of Pharmaceutical Sciences, 2019
Recombinant human interferon beta 1b (rhIFNβ-1b) is clinically used to treat multiple sclerosis. A reversed-phase liquid chromatography (RP-LC) method was carried out on a Jupiter C4 column (250 mm × 4.6 mm i.d.).
Francielle Santos da Silva, Maurício Elesbão Walter, Bruna Xavier, Rafaela Ferreira Perobelli, Guilherme Zanini Calegari, Douglas Franco Cardoso, Valquiria Guedes Perlin, Sérgio Luiz Dalmora   +7 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Efeito de grupos espectadores na hidrólise de diésteres fosfóricos. Estudos da hidrílise do bis-2-piridil fosfato e das reações do fármaco deferoxamina com mono-e triéster de fosfato [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.Esta tese de doutoramento compreende: (i) Estudo das reações de deferoxamina (DFO) com 2,4 ...
Medeiros, Michelle
core  

Signals involved in protein intracellular sorting [PDF]

, 2005
“…Confusion appears to occur just after the articulation of a major conceptual advance that served to greatly clarify a problem of exceptional importance.”- Ira Mellman, 1996.
Nair, Prashant
core   +1 more source