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Bone grafts and biomaterials substitutes for bone defect repair: A review
Bioactive Materials, 2017 Bone grafts have been predominated used to treat bone defects, delayed union or non-union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency of synthetic bone graft substitutes.
Wenhao Wang, Kelvin W.K. Yeung
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Chitosan-Based High-Intensity Modification of the Biodegradable Substitutes for Cancellous Bone
Journal of Functional Biomaterials, 2023 An innovative approach to treating bone defects is using synthetic bone substitutes made of biomaterials. The proposed method to obtain polylactide scaffolds using the phase inversion technique with a freeze extraction variant enables the production of ...
Anna Kołakowska +4 more
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Review of Bone Substitutes [PDF]
Craniomaxillofacial Trauma & Reconstruction, 2009 Bone substitutes are being increasingly used in craniofacial surgery and craniomaxillofacial trauma. We will review the history of the biomaterials and describe the ideal characteristics of bone substitutes, with a specific emphasis on craniofacial reconstruction.
Pryor, Landon +11 more
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Functionalization of Synthetic Bone Substitutes [PDF]
International Journal of Molecular Sciences, 2021 Bone substitutes have been applied to treat osseous defects for a long time. To prevent implant related infection (IRI) and enhance bone healing functionalized biomaterials, antibiotics and osteoinductive substances have been introduced. This study gives an overview of the current available surface-coated bone substitutes and provides an outlook for ...
Busch, André +3 more
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Unfocused shockwaves for osteoinduction in bone substitutes in rat cortical bone defects. [PDF]
PLoS ONE, 2018 Bone substitutes are frequently used in clinical practice but often exhibit limited osteoinductivity. We hypothesized that unfocused shockwaves enhance the osteoinductivity of bone substitutes and improve osteointegration and angiogenesis.
Marianne K E Koolen +5 more
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Journal of Functional Biomaterials, 2021 The inclusion of biofunctional molecules with synthetic bone graft substitutes has the potential to enhance tissue regeneration during treatment of traumatic bone injuries. The clinical use of growth factors has though been associated with complications,
George Bullock +4 more
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Frontiers in Bioengineering and Biotechnology, 2023 Bone substitutes are widely used in maxillofacial and oral surgeries. However, in clinical practice, bone substitutes with various forms, including separated particulates, powders, and blocks, have exhibited poor handling properties and space maintenance
Jiajia Wang +8 more
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Antibiotics, 2022 Antibiotic-laden bone substitutes represent a viable option in the treatment of bone and joint infections with bone defects. In particular, the addition of silver ions or silver nanoparticles to bone substitutes to achieve local antiseptic activity could
Michele Fiore +7 more
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Bone substitutes in vertebroplasty [PDF]
European Spine Journal, 2001 Vertebroplasty--percutaneous cement augmentation of vertebral bodies--is an efficient procedure for the treatment of painful vertebral fractures in osteoporosis. At the present time, polymethylmethacrylate (PMMA) is the only available cement with reports of clinical application and experience.
Heini PF, Berlemann U
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Cyclosporine A impairs bone repair in critical defects filled with different osteoconductive bone substitutes [PDF]
Brazilian Oral Research, 2020 The aim of this study was to assess the influence of cyclosporine administration on the repair of critical-sized calvaria defects (CSDs) in rat calvaria filled with diverse biomaterials. Sixty animals were divided into two groups: the control (CTR) group
Fernanda Castanheira GONÇALVES +5 more
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