Results 41 to 50 of about 88,074 (198)

Mechanistic Illustration: How Newly-Formed Blood Vessels Stopped by the Mineral Blocks of Bone Substitutes Can Be Avoided by Using Innovative Combined Therapeutics

open access: yesBiomedicines, 2021
One major limitation for the vascularization of bone substitutes used for filling is the presence of mineral blocks. The newly-formed blood vessels are stopped or have to circumvent the mineral blocks, resulting in inefficient delivery of oxygen and ...
Fabien Bornert   +17 more
doaj   +1 more source

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]

open access: yes, 2013
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Flinspach, Armin Niklas   +5 more
core   +1 more source

Bone substitutes in vertebroplasty [PDF]

open access: yesEuropean Spine Journal, 2001
Vertebroplasty--percutaneous cement augmentation of vertebral bodies--is an efficient procedure for the treatment of painful vertebral fractures in osteoporosis. At the present time, polymethylmethacrylate (PMMA) is the only available cement with reports of clinical application and experience.
P F, Heini, U, Berlemann
openaire   +2 more sources

Substitutes of Structural and Non-Structural Autologous Bone Grafts in Hindfoot Arthrodeses and Osteotomies: A Systematic Review [PDF]

open access: yes, 2013
Background: Structural and non-structural substitutes of autologous bone grafts are frequently used in hindfoot arthrodeses and osteotomies. However, their efficacy is unclear.
Briel, Matthias   +6 more
core   +1 more source

Osteoconductive Microarchitecture of Bone Substitutes for Bone Regeneration Revisited

open access: yesFrontiers in Physiology, 2018
In the last three decades, all efforts in bone tissue engineering were driven by the dogma that the ideal pore size in bone substitutes lies between 0.3 and 0.5 mm in diameter.
Chafik Ghayor   +3 more
doaj   +1 more source

Graphene for Controlled and Accelerated Osteogenic Differentiation of Human Mesenchymal Stem Cells

open access: yes, 2011
Modern tissue engineering strategies combine living cells and scaffold materials to develop biological substitutes that can restore tissue functions. Both natural and synthetic materials have been fabricated for transplantation of stem cells and their ...
Ahn, Jong-Hyun   +10 more
core   +1 more source

Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates [PDF]

open access: yes, 2017
The design of synthetic bone grafts to foster bone formation is a challenge in regenerative medicine. Understanding the interaction of bone substitutes with osteoclasts is essential, since osteoclasts not only drive a timely resorption of the biomaterial,
Avnet, Sofia   +7 more
core   +2 more sources

Bone Graft Substitutes [PDF]

open access: yes, 2015
__Abstract__ Bone grafting was established in the 19th century and has become a common procedure in which bone defects are filled with bone grafts or bone graft substitutes. Bone defects that require bone grafting are encountered in approximately 10%
Stok, J. (Johan) van der
core  

Preparation, physical-chemical characterisation and cytocompatibility of calcium carbonate cements [PDF]

open access: yes, 2006
The feasibility of calcium carbonate cements involving the recrystallisation of metastable calcium carbonate varieties has been demonstrated. Calcium carbonate cement compositions presented in this paper can be prepared straightforwardly by simply mixing
Aizenberg   +67 more
core   +2 more sources

Comparison of efficacies of different bone substitutes adhered to osteoblasts with and without extracellular matrix proteins

open access: yesJournal of Dental Sciences, 2013
Background/purpose: Regeneration of bony tissue is a major goal in periodontal and implant surgery. The adhesion efficacy of osteogenic cells to bone substitutes is a determinant for osteogenesis.
Li-Ling Tseng   +4 more
doaj   +1 more source

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