Results 51 to 60 of about 25,727 (251)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier   +11 more
wiley   +1 more source

Perspectives on the clinical utility of allografts for bone regeneration within osseous defects: a narrative review

open access: yesOrthopedic Research and Reviews, 2011
Larry E Miller1,2, Jon E Block21Miller Scientific Consulting, LLC, Flagstaff, AZ, USA; 2Jon E. Block, Ph.D., Inc., San Francisco, CA, USAAbstract: A variety of bone grafts and bone graft substitutes is available for treatment of osseous defects although ...
Miller LE, Block JE
doaj  

Preclinical investigation of an innovative magnesium-based bone graft substitute for potential orthopaedic applications

open access: yesJournal of Orthopaedic Translation, 2014
Degradable or corrosive biometal is an attractive research and development (R&D) area in clinical orthopaedics. This study was designed to investigate biomechanical and biological properties of magnesium (Mg) and strontium (Sr) with a focus on Mg-based ...
Chen Liu   +4 more
doaj   +1 more source

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen   +5 more
wiley   +1 more source

Reassessing Bone Marrow Aspirate and Trephine Biopsies in Staging for Paediatric and Young Adult Patients With Ewing Sarcoma and Rhabdomyosarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) are aggressive malignancies in children and adolescents where metastases impact prognosis. 18F‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography/computed tomography (FDG‐PET/CT) and bone marrow aspirate and trephine biopsies (BMAT) are used to identify disease involvement.
Imogen Andrews   +3 more
wiley   +1 more source

Bone Substitutes

open access: yes, 2011
Estomatología
Torres, Jesús   +4 more
openaire   +4 more sources

Review Article: Bone Transplantation and Immune Response

open access: yesJournal of Orthopaedic Surgery, 2009
Bone is the second most common transplant tissue after blood, with the iliac crest autologous graft being most used. Bone transplantation induces osteogenesis to repair bone defects.
Hamid Shegarfi, Olav Reikeras
doaj   +1 more source

Aspergillus fumigatus biofilm formation on different bone substitutes used in maxillary sinus augmentation: an in vitro analysis

open access: yesInternational Journal of Implant Dentistry, 2019
Background Fungus ball (FB) typically affects healthy adults, and Aspergillus fumigatus is the most frequent etiologic agent: iatrogenic factors represent an important issue in FB pathogenesis. Moreover, a recent study suggested a significant association
Claudio Stacchi   +6 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

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