THE UNCHANGEABLE ESSENCE BUT CHANGEABLE AND UNCHANGEABLE ATTRIBUTES [PDF]
In what follows, the author has dealt with the relation between the necessary being as an unchangeable Essence and His changeable and unchangeable attributes.
Ahmad Beheshti
doaj
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Rhetorical Analysis of Semantic Fields of Metaphor in Va'iz Kashifei's prose (Badiye' al Afkar & Anwar i Soheili) [PDF]
Introduction One of the most prominent rhetorical techniques is metaphor, which is used not only in literary poetry and prose, but also in everyday speech, knowingly and unknowingly, and helps the elegance and beauty of speech. This technique, along with
Mahboubeh Moslemizadeh
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Syntactic Analysis of Pronoun Homofunction Considering Verb Structure and the Function of Connected Pronouns in Passive-Emotional Sentences [PDF]
In this research, different word categories are studied which are the reference of mentioned pronouns (i.e. Disconnected or connected), and can substitute pronouns and have pronoun function by deleting them; The reference pronouns of these word ...
Mohammad Irani, Maryam Torkashvand
doaj
Precisely what is Paul referring to in 2 Timothy 1:8 by τὸ μαρτύριον τοῦ κυρίου ἡμῶν? The lexical possibilities for τὸ μαρτύριον and the grammar of the phrase allow at least three possibilities.
Greg A. Couser
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

