Results 81 to 90 of about 468,604 (313)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

WRITING AND LITERARY ACTIVITY IN THE VERNACULAR IN ANGLO-SAXON ENGLAND [PDF]

open access: yes, 2013
У статті розглянуто процес виникнення і функціонування різних форм текстової фіксації на англійських територіальних діалектах давнього періоду розвитку англійської мови як наслідок розвитку суспільних функцій мови та розширення сфер функціонування її ...
Євченко, В. В.
core  

Functional foods: the new concept emerging from the traditional nutrition

open access: yesScripta Scientifica Pharmaceutica, 2015
The present study was aimed to review the scientific evidences that the traditional nutrition of Bulgarians during the centuries could be considered as a dietary pattern with functional characteristics. Historical sources indicated that the diet of our ancestors was low processed, rich in dietary fibers, polyphenols and many other functional components.
Milka Nashar, Diana Ivanova
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcendental Pragmatics and Hermeneutics [PDF]

open access: yes, 2004
: In which sense could transcendental pragmatics combined with a hermeneutical approach provide the social sciences with a critical oriented approach?
Hedberg, Petra
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

AGAMA DAN SOLIDARITAS SOSIAL

open access: yesLisan Al-Hal: Jurnal Pengembangan Pemikiran dan Kebudayaan, 2014
Modern live not always change social behavior be individual. Howeveron the contrary give us a loyalty to traditional tenet that havecommunal characteristic. Traditional festival of Rasulan in GunungKidul Region suspicion that solidarity are preference of
Mohammad Isfironi
doaj  

PARAMETRIC AND NONPARAMETRIC MARKET POWER TESTS: AN EMPIRICAL INVESTIGATION [PDF]

open access: yes
Parametric and nonparametric market power tests most commonly used to assess imperfectly competitive behavior are identified. Monte Carlo experiments are used to assess the accuracy of eight nonparametric tests.
Noelke, Corinna M., Raper, Kellie Curry
core   +1 more source

Solar Deities in the Kuwattalla Ritual Tradition: Epithets and Functions

open access: yes, 2023
Through the contextual analysis of the occurrences of solar deities in the Kuwattalla ritual texts, we will try to sketch a portrait of these deities, focusing on their functions in the ritual process. Special attention will be paid to the combination of ritual gestures with Luwian incantations, since the latter might help to define the specificities ...
openaire   +3 more sources

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