Results 61 to 70 of about 468,604 (313)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Tradizione e metamorfosi della comparatistica

Comparatismi, 2020
L’articolo propone una riflessione sullo statuto attuale della comparatistica letteraria, osservata attraverso il nesso tra tradizione e metamorfosi che caratterizza quest’area di studi anche dal punto di vista internazionale.
Franca Sinopoli
doaj   +1 more source

Theōsis: A Comparative Study of T. F. Torrance and Rāmānuja [PDF]

, 2017
This essay is an imaginative conversation as I engage two religious thinkers—the prolific Reformed theologian Thomas F. Torrance (1913-2007) and the great Vedāntin Rāmānuja (traditionally, 1017–1137).
Tsoukalas, Steven
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Teknonymy in the Anthroponymic System of Northern Athabaskans

Вопросы ономастики, 2020
The paper explores the anthroponymic tradition of teknonymy (paedonymic), renaming a parent by the name of a child, that is common among the northern Na-Dene populations.
Nikita S. Shishelov
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

ACCULTURATION OF ISLAMIC CULTURE AND LOCAL CULTURE IN DRUMING TRADITION IN PANJANG REGION VILLAGE, KUCHING, SARAWAK, MALAYSIA

Batuthah
This article focuses on the acculturation of Islamic culture and local culture in the Bergendang tradition. The purpose of writing this article is to preserve the traditions that have been carried out by the Rantau Panjang Malay community in order to ...
Mohammad Shafiq Bin Asan
doaj   +1 more source

Eksistensi Mutu Pendidikan Informal Bali Aga Era Revolusi Industri 4.0

Jurnal Penjaminan Mutu, 2020
As the Balinese people of Bali Aga, the people of Tenganan Peringsingan custom village had a special characteristics and identities than Balinese people in common.
I Nengah Juliawan
doaj   +1 more source

Development, Research and Sources of Written Livonian; pp. 55-67 [PDF]

Linguistica Uralica, 2012
Written Livonian started forming in the mid-19th century, when the first more comprehensive language studies as well as editions containing language samples began to be published.
Valts Ernštreits
doaj   +1 more source