Results 51 to 60 of about 24,599 (245)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Tradizione e metamorfosi della comparatistica

open access: yesComparatismi, 2020
L’articolo propone una riflessione sullo statuto attuale della comparatistica letteraria, osservata attraverso il nesso tra tradizione e metamorfosi che caratterizza quest’area di studi anche dal punto di vista internazionale.
Franca Sinopoli
doaj   +1 more source

Folk Traditions of Lullabies: Functional Analysis [PDF]

open access: yesGlobal Sociological Review, 2019
Lullabies are known as a genre of music for infants, which are performed at the sleep time of the child by the parent, usually mothers or by the caregivers. The present study is an attempt to understand the functions it fulfils in a cultural context and its evolution to the present day by the lived experiences of forty-seven Pakistani parents.
Sohima Anzak   +2 more
openaire   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Teknonymy in the Anthroponymic System of Northern Athabaskans

open access: yesВопросы ономастики, 2020
The paper explores the anthroponymic tradition of teknonymy (paedonymic), renaming a parent by the name of a child, that is common among the northern Na-Dene populations.
Nikita S. Shishelov
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Analisis Resepsi Fungsional dalam Tradisi Pembacaan 124.000 Surah al-Ikhlas di Desa Pangkatrejo Lamongan

open access: yesJavano Islamicus
This study examines the practice of Living Qur'an in the form of reading 124,000 times surah al-Ikhlāṣ in a series of deaths in Pangkatrejo Village, Lamongan.
Ahmad Fikri
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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