Results 71 to 80 of about 29,162 (288)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Folk Traditions of Lullabies: Functional Analysis [PDF]
Global Sociological Review, 2019 Lullabies are known as a genre of music for infants, which are performed at the sleep time of the child by the parent, usually mothers or by the caregivers. The present study is an attempt to understand the functions it fulfils in a cultural context and its evolution to the present day by the lived experiences of forty-seven Pakistani parents.
Sohima Anzak +2 more
openaire +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Synchronous Digital Circuits as Functional Programs [PDF]
, 2014 Functional programming techniques have been used to describe synchronous digital circuits since the early 1980s and have proven successful at describing certain types of designs.
Peter Gammie
core
The politics of tradition in Baluan social change and the construction of the past in a Manus society [PDF]
, 2017 In this thesis I explore the recent historical development of Saluan culture. I begin by arguing that the sphere of cultural phenomena must not be regarded as a coherent unity.
Otto, Ton
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Eksistensi Mutu Pendidikan Informal Bali Aga Era Revolusi Industri 4.0
Jurnal Penjaminan Mutu, 2020 As the Balinese people of Bali Aga, the people of Tenganan Peringsingan custom village had a special characteristics and identities than Balinese people in common.
I Nengah Juliawan
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Authority of the Father: Eternal functional subordination – Quo Vadis?
, 2021 This article aims to provide the reader with a short introduction on, and overview of the movement called Eternal Functional Subordination (EFS) that wasintroduced in 1977 by a Presbyterian preacher, George Knight.
W.H. Oliver, Oliver, W.H.
core +1 more source