Results 171 to 180 of about 11,640,478 (268)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The Development of Selective Attention in Children's Emotion Reasoning. [PDF]

Dev Sci
Stein AG, Pollak SD.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

miR-146a/b-5p-IRAK1-NF-κB Axis Regulates Unexplained Recurrent Spontaneous Abortion. [PDF]

J Mol Recognit
He F, Fan S, Chen L, Lou J, Lin Z, Liu Y, Yan T, Zhang Y.   +7 more
europepmc   +1 more source

Implementation and Outcomes of Peer Support Workers in Services for People With Personality Disorder: A Systematic Review and Narrative Synthesis. [PDF]

Personal Ment Health
Begum-Meades R, Guillemard S, Limbachiya R, Lean E, Thompson F, Crawford MJ.   +5 more
europepmc   +1 more source

Non-Symbolic Magnitude Processing Is a Strong Correlate of Symbolic Math Skills in Children From Ghana and Côte d'Ivoire. [PDF]

Dev Sci
Bugden S, Ansari D, Lichand G, Avornyo EA, Wolf S.   +4 more
europepmc   +1 more source

δ¹³C and δ¹⁵N Values of Residues Provide Insights Into Identification of the Explosive Source. [PDF]

Rapid Commun Mass Spectrom
Ehleringer JR, Howa JD.
europepmc   +1 more source

Levosimendan vs. Intra-Aortic Balloon Pump in Coronary Artery Bypass Grafting: A Meta-Analysis. [PDF]

Braz J Cardiovasc Surg
Wang Y, Qu J, Sheng D, Sun X, Zhong L, Wu Y, Liang H.   +6 more
europepmc   +1 more source

Inflammatory Mediators Both Directly and Indirectly Promote Microglial Proliferation. [PDF]

Glia
Hammond BP, Hahn E, Lee KV, Kerr BJ, Plemel JR.   +4 more
europepmc   +1 more source

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Non-covalent interaction of soy protein isolate and catechin: Mechanism and effects on protein conformation.

Food Chemistry, 2022
Understanding the molecular mechanism behind protein-polyphenol interactions is critical for the application of protein-polyphenol compounds in foods.
Shicheng Dai, Ziteng Lian, Weijie Qi, Yashuang Chen, Xiaohong Tong, Tian Tian, Bo Lyu, Mengmeng Wang, Huan Wang, Lianzhou Jiang   +9 more
semanticscholar   +1 more source