Bioinformatic Analysis and Molecular Docking Identify Isorhamnetin Is a Candidate Compound in the Treatment of Pulmonary Artery Hypertension. [PDF]
Shao C, Xia W, Liu Y.
europepmc +1 more source
Antagonism by naloxone (N) of tolerance (T) and dependence (D) in mice treated with morphine (M)
Ichiro Yano, Tadashi MURANO
openalex +1 more source
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu+7 more
wiley +1 more source
'Nothing to lose or a world to win': Reconsidering efficacy, legitimacy, political trust and repression in confrontational collective action. [PDF]
Uysal MS, Drury J, Acar YG.
europepmc +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Intraoperative and Short-Term Postoperative Outcomes Associated With Transoral Robotic Surgery: A Protocol for a Scoping Review. [PDF]
Larsen AA+6 more
europepmc +1 more source
Influence of naloxone on the total capacitance vasculature of the dog. [PDF]
L. B. Bell, Edward Maratea, D. L. Rutlen
openalex +1 more source
"Tractatus linguistico-therapeuticus" : towards a theory of therapeutic language 1 [PDF]
Jemmer, Patrick
core
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source