Results 201 to 210 of about 11,054,575 (256)

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

What stroke survivors say about living with upper limb spasticity and how they manage it. [PDF]

Aust Occup Ther J
Pike S, Lannin NA, Cameron L, Palit M, Schneider E, Cusick A.   +5 more
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Tools for Evaluating Potentially Inappropriate Medication Use in Older Adults: A Scoping Review Assessing Suitability for Register-Based Research. [PDF]

Basic Clin Pharmacol Toxicol
Mose K, Lundby C, Rasmussen L, Pottegård A.   +3 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Tissue and Salivary NMR Metabolomics in Reticular-Type Oral Lichen Planus. [PDF]

NMR Biomed
Setti G, Gambini A, Righi V, Mucci A, Pertinhez TA, Ferrari E, Gallo M, Biscussi B, Antonelli R, Meleti M, Magnoni C.   +10 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Spontaneous Malignant Peripheral Nerve Sheath Tumour in a Captive Rhesus Macaque (Macaca mulatta). [PDF]

J Med Primatol
Barro MV, Herford JD, Garzel LM, Chu P, Reader JR.   +4 more
europepmc   +1 more source

Design of Automatic Tool Replacement Mechanism for Laparoscopic Surgical Robot Arm for Solo Surgery. [PDF]

Int J Med Robot
Ko D, Kim Y, Lim H, Kim S.
europepmc   +1 more source

Nitrogen Substrate Impacts Microcystis aeruginosa Exometabolome Composition. [PDF]

Environ Microbiol Rep
Peck CM, Hart LN, Kersten R, Kharbush JJ.   +3 more
europepmc   +1 more source