Results 221 to 230 of about 11,054,575 (256)
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Absorption of naloxone in patients prescribed buprenorphine‐naloxone
The American Journal on AddictionsAbstractBackground and ObjectivesWhen administered as prescribed, the naloxone component of buprenorphine‐naloxone combination medications is putatively considered inert due to reduced naloxone bioavailability via transmucosal. However, there is a growing body of evidence to the contrary.
Ian Michel+5 more
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Nociceptive circling and naloxone
Pharmacological Research Communications, 1983Under suitable conditions, mice exhibit rotatory behaviour, with a direction preference. Noxious electric stimulation to the feet of mice was found to increase significantly the rate of turning, as well as the ratio between circling in the preferred and in the opposite direction (the latter change was not significant statistically).
R. Rabinowitz+2 more
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Naloxone enhancement of memory
Behavioral and Neural Biology, 1979Naloxone enhanced retention when systemically administered to male F344 rats after training in a one-trial inhibitory avoidance task. Further, the memory-enhancing ability of naloxone appears to be opiate receptor dependent, because it was antagonized by morphine. Naloxone also improved retention of rats in an active avoidance task, indicating that the
Robert A. Jensen+7 more
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Naloxone-precipitated withdrawal as a function of the morphine-naloxone interval
Psychopharmacology, 1977Withdrawal was precipitated by naloxone at different intervals, up to 22.5 h, following a last maintenance injection in morphine-dependent rats. Different symptoms of withdrawal were found to be preeminent following different morphine-naloxone intervals.
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Annals of Internal Medicine, 1983
Excerpt To the editor: We read with interest the report by Higgins and associates (1) on the reversal of hypotension by continuous infusion of naloxone in a ventilator-dependent patient.
Hughes Gs, Harker Cc, Marx R, Porter Rs
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Excerpt To the editor: We read with interest the report by Higgins and associates (1) on the reversal of hypotension by continuous infusion of naloxone in a ventilator-dependent patient.
Hughes Gs, Harker Cc, Marx R, Porter Rs
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Naloxone and intestinal motility
Experientia, 1978It was supposed that the inhibition of intestinal peristalsis seen in animals and humans after abdominal surgery might be related to the release of endorphins, endogenous opiate receptor agonists, caused by the surgical stress and pain. However, naloxone, a potent morphine and endorphin antagonist, failed to block this peristaltic inhibition in rats ...
A. Palekar, A. Adamovics, R. A. Howd
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Naloxone, Meperidine, and Shivering
Anesthesiology, 1993Meperidine, which binds both mu and kappa opioid receptors, is reportedly more effective in treating shivering than are equianalgesic doses of morphine (a nearly pure mu-receptor agonist). Furthermore, butorphanol, a kappa-receptor agonist/antagonist, treats shivering better than does fentanyl, which mostly binds mu receptors.
Martin Kurz+6 more
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Critical Care Medicine, 1983
Naloxone, 0.3 mg/kg of a 10 mg/ml solution, was administered as a single bolus to patients in septic shock if their systolic blood pressure (BP) was less than 100 mm Hg or MAP less than 70 mm Hg with evidence of renal or cerebral hypoperfusion. Patients with chronic or acute (less than 12 h) administration of narcotics were excluded.
William S. Howland+2 more
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Naloxone, 0.3 mg/kg of a 10 mg/ml solution, was administered as a single bolus to patients in septic shock if their systolic blood pressure (BP) was less than 100 mm Hg or MAP less than 70 mm Hg with evidence of renal or cerebral hypoperfusion. Patients with chronic or acute (less than 12 h) administration of narcotics were excluded.
William S. Howland+2 more
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C&EN Global Enterprise, 2016
The emergency call came in simply as a person down. It could have meant any number of things, says former Atlanta-area paramedic Kevin Hazzard. The patient might have been a diabetic whose blood sugar was too low or someone who’d had too much to drink. But when Hazzard arrived on the scene, it was clear the young woman had overdosed on heroin. “She was
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The emergency call came in simply as a person down. It could have meant any number of things, says former Atlanta-area paramedic Kevin Hazzard. The patient might have been a diabetic whose blood sugar was too low or someone who’d had too much to drink. But when Hazzard arrived on the scene, it was clear the young woman had overdosed on heroin. “She was
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Gastroenterology Nursing, 1989
The gastroenterology nurse must be familiar with the use of Narcan. Narcan is frequently administered in the endoscopy suite after the procedure for the reversal of narcotic depression induced by pre-procedure intravenous sedation. Knowledge of Narcan will allow the nurse to safely administer the medication as well as adequately assess the patient's ...
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The gastroenterology nurse must be familiar with the use of Narcan. Narcan is frequently administered in the endoscopy suite after the procedure for the reversal of narcotic depression induced by pre-procedure intravenous sedation. Knowledge of Narcan will allow the nurse to safely administer the medication as well as adequately assess the patient's ...
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