Results 231 to 240 of about 278,683,873 (354)

Microiontophoretic application of morphine and naloxone to neurons in hypothalamus of rat

, 1984
Bertha Prieto-Gómez, C. Reyes‐Vázquez, Nachum Dafny   +2 more
openalex   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

From Retention Time to Functional Group Assignment: A Chemical Database-Driven Approach for High-Resolution Mass Data of Marine Dissolved Organic Matter. [PDF]

Rapid Commun Mass Spectrom
Moye F, Bareth M, Koch BP, Tebben J, Harder T.   +4 more
europepmc   +1 more source

Naloxone Does Not Modify the Hemodynamic and Neuroendocrine Effects of Clonidine in Normal Humans

, 1985
Roberto Pedrinelli, Gianpaolo Bernini, Antonio Salvetti   +2 more
openalex   +1 more source

National learner satisfaction survey: apprentices report (BIS research paper number 19) [PDF]

, 2011
Klein, Angela, Lambert, Claire, Lister, Claire, Taylor, Billie Lever, Tu, Trinh   +4 more
core  

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Optimisation of Heated Electrospray Ionisation Parameters to Minimise In-Source Generated Impurities in the Analysis of Oligonucleotide Therapeutics. [PDF]

Rapid Commun Mass Spectrom
Glenister MA, Mistarz U, Cook K, Stephenson JL, Dickman MJ.   +4 more
europepmc   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Healthcare, solidarity, and moral community in Myanmar's humanitarian crisis and revolution. [PDF]

Disasters
Décobert A.
europepmc   +1 more source

Options study for the long-term evaluation of apprenticeships [PDF]

, 2011
Elias, Peter, Gambin, Lynn, Hasluck, Chris, Hogarth, Terence, Ryan, Paul   +4 more
core