Results 101 to 110 of about 26,541 (195)

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Phenol-Rich Carbon Dots as Metal-Free Nano-Photocatalysts for [3 + 2] Cycloaddition Reactions. [PDF]

ChemSusChem
Mamone M, Gentile G, Prato M, Filippini G.   +3 more
europepmc   +1 more source

A dual-engineered covalent organic framework with charge-oxygen synergy promotes photocatalytic dipolar [3 + 2] cycloaddition. [PDF]

Chem Sci
Liu Y, Shen L, Yang H, Zhao X, Lan X.
europepmc   +1 more source

[3 + 2] Cycloaddition of thioformylium methylide with various arylidene-azolones in the synthesis of 7-thia-3-azaspiro[4.4]nonan-4-ones. [PDF]

Beilstein J Org Chem
Rudik DI, Tiushina IV, Sokolov AI, Smirnov AY, Romanenko AR, Korlyukov AA, Mikhaylov AA, Baranov MS.   +7 more
europepmc   +1 more source

Mechanistic insights into the (3 + 2) cycloaddition of azomethine ylide with dimethyl acetylenedicarboxylate <i>via</i> bond evolution theory. [PDF]

RSC Adv
Chellegui M, Al-Mokhtar RM, Salih RN, Benhamed L, Benmetir S, Vicente de Julián-Ortiz J, Mohammad-Salim HA, Ben Ahmed A.   +7 more
europepmc   +1 more source

[3+2] Cycloaddition to a Chiral 5-Methylene-1,3-dioxolan-4-one and Pyrolysis of the Spiro Adducts. [PDF]

Molecules
Aitken RA, Power LA, Slawin AMZ.
europepmc   +1 more source

Glycine-Based [3+2] Cycloaddition for the Synthesis of Pyrrolidine-Containing Polycyclic Compounds. [PDF]

Molecules
Zhou T, Zhang X, Zhan D, Zhang W.
europepmc   +1 more source

Synthesis of a Stable Hydrophilic trans‐Cyclooctene Amino Acid Unlocks Fast Bioorthogonal Click Chemistry for the Generation of Antibody‐Drug Conjugates by Genetic Code Expansion

Angewandte Chemie International Edition, EarlyView.
A novel trans‐cyclooctene (TCO) based noncanonical amino acid (ncAA) is reported, characterized by high hydrophilicity and remarkable stability to trans‐cis isomerization. Its incorporation via genetic code expansion into an antibody and subsequent conjugation resulted in a highly efficacious antibody‐drug conjugate (ADC).
Georgi R. Genov, Dina Osmanović, Ines Bašić, Christine Koehler, Paul F. Sauter   +4 more
wiley   +1 more source

Synthesis of Complex Tetracyclic Fused Scaffolds Enabled by (3 + 2) Cycloaddition. [PDF]

Org Lett
Porte V, van Veen BC, Zhang H, Piacentini P, Matheu SA, Woolford S, Sokol KR, Shaaban S, Shaaban S, Weinstabl H, Maulide N.   +10 more
europepmc   +1 more source

On the Question of the Regio-, Stereoselectivity and the Molecular Mechanism of the (3+2) Cycloaddition Reaction Between (<i>Z</i>)-C-Phenyl-N-alkyl(phenyl)nitrones and (<i>E</i>)-3-(Methylsulfonyl)-propenoic Acid Derivatives. [PDF]

Molecules
Ząbkowska M, Kula K, Diychuk V, Jasiński R.   +3 more
europepmc   +1 more source