Results 41 to 50 of about 1,071 (121)

Beyond the Biopsy: Imaging Frontiers in Cardiac Sarcoidosis

open access: yesCardiology Research and Practice, Volume 2026, Issue 1, 2026.
Cardiac sarcoidosis (CS) represents an inflammatory infiltrative disease, which creates difficulties during diagnosis and prognosis. The identification and management of CS heavily depend on advanced cardiac imaging techniques. The article examines multimodality imaging in CS by evaluating cardiac magnetic resonance (CMR) imaging, positron emission ...
Ibrahim Antoun   +5 more
wiley   +1 more source

Clinical Application of Positron Emission Tomography/Magnetic Resonance Imaging in Pelvic Malignant Tumors

open access: yesiRADIOLOGY, Volume 3, Issue 6, Page 421-433, December 2025.
The article reviews the application of positron emission tomography/magnetic resonance imaging (PET/MRI) in pelvic tumors such as endometrial cancer, cervical cancer, ovarian cancer, prostate cancer, and bladder cancer. We summarize the comparative studies on the clinical application between PET/CT and PET/MRI to highlight the advantages and ...
Hui Yang   +7 more
wiley   +1 more source

Advances in the Diagnosis, Treatment, and Management of Liver Nodules: A Comprehensive Review

open access: yesPortal Hypertension &Cirrhosis, Volume 4, Issue 4, Page 232-251, December 2025.
Liver nodules commonly occur due to various causes, some of which are malignant or may undergo malignant transformation, leading to disease progression or delayed detection in clinical practice. The widespread use of imaging methods has increased the detection rate of liver nodules. Furthermore, precision medicine techniques and artificial intelligence
Chang Gao, Dongyang Chen, Youpeng Chen
wiley   +1 more source

Advances in radiopharmaceuticals for cancer radiotheranostics: CCK2R targeting as a paradigm for translational innovation

open access: yesCancer Communications, Volume 45, Issue 11, Page 1431-1455, November 2025.
Abstract Radiopharmaceuticals are reshaping the landscape of cancer therapy, offering a unique theranostic advantage that is becoming increasingly central to precision medicine. By labeling the same molecular scaffold with different radionuclides, these agents enable seamless integration of diagnostic imaging and targeted therapy.
Jing Li   +6 more
wiley   +1 more source

Feasibility of early-phase [68Ga]Ga-FAPI-46 PET for preoperative staging in lung cancer

open access: yes
Abstract Background Fibroblast activation protein (FAP)-targeting PET has gained attention in oncology for its high diagnostic performance and procedural advantages, including the possibility of early image acquisition. This study investigated the feasibility of early-phase [ 68 Ga]
Yeon-koo Kang   +4 more
openaire   +1 more source

Radiolabelled Cyclodextrins for the Positron Emission Tomography Imaging of Breast Cancer: Preclinical Perspectives

open access: yesClinical and Translational Science, Volume 18, Issue 10, October 2025.
ABSTRACT Given the increasing incidence and mortality of breast cancer, the development of target‐specific imaging probes for early disease detection seems straightforward. Prostaglandin E2 (PGE2) and its receptors have a crucial role in tumor angiogenesis; therefore, radiolabelled cyclodextrins targeting such biomolecules may serve as selective ...
Tamás Sass   +10 more
wiley   +1 more source

Emerging Radiopharmaceuticals Beyond FDG for Ovarian Cancer: A Review of Advances in Nuclear Medicine

open access: yesCancer Medicine, Volume 14, Issue 17, September 2025.
Emerging radiopharmaceuticals in nuclear medicine could improve ovarian cancer diagnosis and staging, while also enabling assessment of treatment response, therapy resistance, and suitability for targeted therapies. ABSTRACT Aims This review summarizes the role and future prospects of nuclear medicine in ovarian cancer, focusing on novel ...
Mara M. K. Veenstra   +7 more
wiley   +1 more source

Cancer‐Associated Fibroblasts: Heterogeneity, Cancer Pathogenesis, and Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Cancer‐associated fibroblasts (CAFs) arise from normal fibroblasts in response to various tumor microenvironmental signals, including cytokines such as TGF‐β and IL‐6, paracrine factors like PDGFs, Notch signaling, extracellular vesicles, as well as aging, inflammation, hypoxia, oxidative stress, and increased extracellular matrix (ECM) stiffness. Upon
Yutao Li   +6 more
wiley   +1 more source

[68Ga]Ga-FAPI-46 PET accuracy for cancer imaging with histopathology validation: a single-centre, single-arm, interventional, phase 2 trial

open access: yesThe Lancet Oncology
The fibroblast activation protein α (FAP)-directed radiotracer [68Ga]Ga-FAPI-46 for PET-CT has shown promising diagnostic accuracy in cancer staging in retrospective studies. We aim to investigate the positive predictive value (PPV) of [68Ga]Ga-FAPI-46 PET for detecting FAP-expressing tumours and the potential association between PET radiotracer uptake
Kim M Pabst   +26 more
openaire   +2 more sources

Intra-patient comparison of tracer uptake and biodistribution of [68Ga]Ga-FAPI-46 and  [18F]AlF-FAPI-74

open access: yes
Abstract Purpose To compare the tracer uptake and biodistribution of [ 68 Ga]Ga-FAPI-46 and [ 18 F]AlF-FAPI-74 in an intra-patient study design.
Anne-Leen Deleu   +12 more
openaire   +1 more source

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