Results 11 to 20 of about 9,822 (215)

In-school and/or out-of-school computer science learning influence on CS career interests, mediated by having role-models

Computer Science Education, 2023
Background and Context Both in- and out-of-school computer science (CS) learning opportunities are expanding, but their influences on CS career interests are unclear.
Chen Chen, J. Rothwell, P. Maynard-Zhang
semanticscholar   +1 more source

Computer Science Curricula 2023 (CS2023): Community Engagement by the ACM/IEEE-CS/AAAI Joint Task Force

Technical Symposium on Computer Science Education, 2022
A Joint Task Force of the ACM, IEEE-Computer Society, and AAAI commenced work in 2021 to revise the Computer Science curricular guidelines that were last updated in 2013.
Amruth N. Kumar, Rajendra K. Raj
semanticscholar   +1 more source

Computer science (CS) in the compulsory education curriculum: Implications for future research

Education and Information Technologies : Official Journal of the IFIP technical committee on Education, 2016
The subject of computer science (CS) and computer science education (CSE) has relatively recently arisen as a subject for inclusion within the compulsory school curriculum.
D. Passey
semanticscholar   +1 more source

Does Curricular Complexity in Computer Science Influence the Representation of Women CS Graduates?

Technical Symposium on Computer Science Education
Not all degree programs are created equal. Indeed, the structure, prerequisites and overall complexity of some programs create barriers that impede student success.
Albert Lionelle, Mckenna Quam, Carla E. Brodley, Catherine Gill   +3 more
semanticscholar   +1 more source

Promoting and Supporting Computer Science Among Middle School Girls of Color: Initial Findings from BRIGHT-CS

Technical Symposium on Computer Science Education, 2020
BRIGHT-CS (Building Student Retention through Individuated Guided coHort Training in Computer Science) is a research and development project that 1) creates a computer science learning ecosystem for middle school Black girls and other girls of color and ...
V. Madrigal, Ryoko Yamaguchi, Adam Hall, Jamika D. Burge   +3 more
semanticscholar   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

'Do I Have to Take This Class?': A Review of Ethics Requirements in Computer Science Curricula

Technical Symposium on Computer Science Education
ABET criteria for accreditation of undergraduate computer science (CS) degrees require universities to cover within their curricula topics including ''local and global impacts of computing solutions on individuals, organizations, and society,'' and to ...
James Weichert, Dayoung Kim, Qin Zhu, Hoda Eldardiry   +3 more
semanticscholar   +1 more source