Results 61 to 70 of about 26,789,071 (219)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The Directional p-Median Problem with Applications to Traffic Quantization and Multiprocessor Scheduling

open access: yes, 2004
An instance of a p-median problem gives n demand points. The objective is to locate p supply points in order to minimize the total distance of the demand points to their nearest supply point. P-median is polynomially solvable in one dimension but NP-hard
Jackson, Laura Elizabeth
core  

Analysis of Facility Protection Strategies Against Uncertain Numbers of Attacks: The Stochastic R-Interdiction Median Problem with Fortification [PDF]

open access: yes, 2008
We present the Stochastic R-Interdiction Median Problem with Fortification (S-RIMF). This model optimally allocates defensive resources among facilities to minimize the worst-case impact of an intentional disruption. Since the extent of terrorist attacks
Liberatore, Federico   +5 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A note on Condorcet consistency and the median voter [PDF]

open access: yes
We discuss to which extent the median voter theorem extends to the domain of single-peaked preferences on median spaces. After observing that on this domain a Condorcet winner need not exist, we show that if a Condorcet winner does exist, then it ...
Buechel, Berno
core  

Median Inpatient Prevalence Rates per 100 people and Median Inpatient Counts, by Medical Category.

open access: yes, 2015
Note: Median inpatient prevalence rates/median inpatient counts for each medical category and overall are presented, along with the interquartile range (IQR). Median inpatient prevalence rates/median inpatient counts are interpreted at the zip code level.
Marilyn Howarth (770739)   +12 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Median-joining network of the 66 cox1 haplotype sequences of Rickettsia positive and negative H. flava.

open access: yes
Median-joining network of the 66 cox1 haplotype sequences of Rickettsia positive and negative H. flava.
Tsutomu Tamura (6195320)   +6 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy