Results 71 to 80 of about 26,789,071 (219)

Présentation du programme MeDIan (2010-2013)

open access: yes, 2010
PRÉSENTATION DU PROGRAMME Le programme MeDIan envisage l'océan Indien comme objet d'étude et de connaissance dans les sociétés méditerranéennes, de ses premières mentions dans les sources grecques sous le nom de mer Érythrée, jusqu'à la fin du XVIe s. On
median
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Median Stable Matching [PDF]

open access: yes
We define the median stable matching for two-sided matching markets with side payments and prove constructively that it exists.
Michael Schwarz, M. Bumin Yenmez
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Single-Crossing, Strategic Voting and the Median Choice Rule [PDF]

open access: yes
This paper studies the strategic foundations of the Representative Voter Theorem (Rothstein, 1991), also called the "second version" of the Median Voter Theorem. As a by-product, it also considers the existence of non-trivial strategy-proof social choice
Alejandro Saporiti, Fernando Tohmé
core  

Median 17-beta-estradiol level.

open access: yes, 2013
Median 17-beta-estradiol level.
Christine Galant (428241)   +8 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Observed and regressed median PlGF MoM in Down syndrome pregnancies according to gestational age.

open access: yes, 2012
*Median MoM at completed week (week+3 days).**Regressed median MoM at 135.5 days gestation (median gestational at 18–22 completed weeks).
Jonathan P. Bestwick (130538)   +3 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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