Results 81 to 90 of about 26,789,071 (219)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Robust p-median problem in changing networks [PDF]
, 2015 The robust p-median problem in changing networks is a version of known discrete p-median problem in network with uncertain edge lengths where uncertainty is characterised by given interval.
Štefan PEŠKO, Tomáš MAJER
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
An empirical application of the median voter model and of the interest group influence model to the Portuguese and Galician municipalities [PDF]
The analysis of the median voter hypothesis indicates that a more realistic comprehension of local public choice might be achieved with the opening of the median voter model to the interst group influence hypothesis.
José Cruz
core
Median (range) and p-values for the transcription of target genes within skin samples.
, 2015 Significant Bonferroni corrected p-values are highlighted bold (p< = α/3).(*)p ...
Karin Allenspach (335040) +5 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Weighted Repeated Median Smoothing and Filtering [PDF]
We propose weighted repeated median filters and smoothers for robust non-parametric regression in general and for robust signal extraction from time series in particular.
Fried, Roland +2 more
core
Median (range) and p-values for the transcription of target genes within lymph node samples.
, 2015 Significant Bonferroni corrected p-values are highlighted bold (p< = α/3).(*)p ...
Karin Allenspach (335040) +5 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Median (range) and p-values for the transcription of target genes within spleen samples.
, 2015 Significant Bonferroni corrected p-values are highlighted bold (p< = α/3).(*)p ...
Karin Allenspach (335040) +5 more
core +1 more source