Results 31 to 40 of about 7,591,664 (247)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Spatiotemporal Feature Fusion Using U-Shaped Architecture for Accurate Wind Speed Prediction

Algorithms
Accurate wind speed forecasting plays a crucial role in the safe and stable operation of wind farms and the efficient integration of renewable energy into modern power systems.
Yue Gao, Zhongda Tian
doaj   +1 more source

ensemblQueryR: fast, flexible and high-throughput querying of Ensembl LD API endpoints in R

GigaByte, 2023
We present ensemblQueryR, an R package for querying Ensembl linkage disequilibrium (LD) endpoints. This package is flexible, fast and user-friendly, and optimised for high-throughput querying.
Aine Fairbrother-Browne , Sonia García-Ruiz , Regina Hertfelder Reynolds , Mina Ryten , Alan Hodgkinson   +4 more
doaj   +1 more source

Chatter Control by Spindle Speed Variation in High-Speed Milling [PDF]

, 2009
High-speed milling operations are often limited by regenerative vibrations. The aim of this paper is to analyze the effect of spindle speed variation on machine tool chatter in high-speed milling. The stability analysis of triangular and sinusoidal shape
Arnaud, Lionel, Insperger, Tamás, Seguy, Sébastien, Dessein, Gilles   +3 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

A novel dynamic spatio-temporal graph convolutional network with multi-scale transformer for high-resolution wind vector forecasting

Energy Conversion and Management: X
Accurate wind speed forecasting is crucial for the grid integration of wind farms and the dispatch of power systems. However, due to the inherent randomness and variability of wind speed, achieving high-precision wind speed forecasting (WSF) remains a ...
Guangsen Huang, Huan Li, Xinyue Mo, Xiangyu Jian   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Wind Speed Multi-Step Forecasting Using High- Resolution and Multi-Objective Ensemble Model With Error Correction

IEEE Access
Accurate wind forecasting is essential for enhancing the stability and efficiency of wind power systems. However, the nonlinear and unstable characteristics of wind pose significant challenges to achieving high-performance predictions in this domain.
Shengcai Zhang, Changsheng Zhu, Xiuting Guo   +2 more
doaj   +1 more source

Radar Signal Processing Method of Space-Time-Frequency Focus-Before-Detects

Leida xuebao, 2014
For the high-speed, high-maneuverability and stealthy target detection via modern radar in complicated electromagnetic environment, a novel radar signal processing approach called Space-Time-Frequency Focus-Before-Detection (STF-FBD) via multi ...
Xu Jia, Peng Ying-ning, Xia Xiang-gen, Long Teng, Mao Er-ke   +4 more
doaj   +1 more source