Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Valtion tutkimuslaitoksissa työskentelevien tutkijoiden julkaisemisen ja lukemisen käytännöt
Elina Late
doaj
Effects of early vs. late administration of labetalol on maternal cerebral perfusion and fetal growth in severe pre-eclampsia. [PDF]
Wang J, Yu F.
europepmc +1 more source
Pervasive Desiccation of North American Lakes During the Late Quaternary
David Liefert, Bryan N. Shuman
openalex +2 more sources
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The effect of dumping syndrome severity on health-related quality of life among bariatric surgery patients in Saudi Arabia. [PDF]
Baghdadi LR +5 more
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Conserved 'Late' Effector Genes From Leptosphaeria maculans Inducing Gene-For-Gene Quantitative Resistance in Brassica napus Semi-Winter Genotypes. [PDF]
Rabeau C +5 more
europepmc +1 more source
35.5L: Late‐News Paper : A Direct‐View MEMS Display for Mobile Applications [PDF]
Nesbitt W. Hagood +7 more
openalex +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source

