Results 1 to 10 of about 523 (88)
Some of the next articles are maybe not open access.

Mitophagy in Hypertensive Cardiac Hypertrophy: Mechanisms and Therapeutic Implications. [PDF]

open access: yesJ Clin Hypertens (Greenwich)
ABSTRACT Hypertensive cardiac hypertrophy (HCH) is a compensatory response to chronic pressure overload, ultimately progressing to heart failure if left unmanaged. Emerging evidence highlights the critical role of mitochondrial dysfunction in HCH pathogenesis, with impaired mitophagy—a selective autophagic process that removes damaged mitochondria ...
Li S, Li X.
europepmc   +2 more sources

CHB-Induced Immune Zonation Chaos Elicited LXRα-mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation. [PDF]

open access: yesAdv Sci (Weinh)
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Shi J   +18 more
europepmc   +2 more sources

Determinants of maximal oxygen uptake in highly trained females and males: a mechanistic study of sex differences using advanced invasive methods

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo   +11 more
wiley   +1 more source

Shared Spectral Parameters Between EEG and Basal Ganglia LFP Distinguish Sleep‐Specific Oscillations in Parkinson's Disease

open access: yesEuropean Journal of Neurology, Volume 33, Issue 9, September 2026.
In 19 people with Parkinson's disease and STN‐DBS, aperiodic features of cortical EEG and STN LFP tracked one another across full nights of polysomnography‐scored sleep. Aperiodic offset and slope distinguished wakefulness from sleep, and STN‐LFP features alone classified sleep stages as accurately as combined STN‐LFP and EEG.
Lisa Hirt   +11 more
wiley   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 7, July 2026.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng   +6 more
wiley   +1 more source

A Tutorial on Bayesian Multi‐Study Factor Analysis With Applications in Nutrition and Genomics

open access: yesStatistics in Medicine, Volume 45, Issue 10-12, May 2026.
ABSTRACT High‐dimensional data are crucial in biomedical research. Integrating such data from multiple studies is a critical process that relies on the choice of advanced statistical models, enhancing statistical power, reproducibility, and scientific insight compared to analyzing each study separately.
Mavis Liang   +3 more
wiley   +1 more source

Engineered Cellulose: A Multifunctional Platform for Next‐Generation Sustainable Environmental Technologies

open access: yesEcoMat, Volume 8, Issue 4, April 2026.
Engineered cellulose—enabled by functionalization, hybridization, and nano‐engineering—emerges as a versatile platform driving next‐generation solutions in water purification, CO2 capture, air filtration, soil remediation, energy storage, and sustainable packaging. ABSTRACT Engineered cellulose is redefining the frontier of sustainable materials in the
Amir Hossein Behroozi   +1 more
wiley   +1 more source

Cambios en las concentraciones de compuestos organoclorados en las mujeres de Flix, Tarragona Changes in concentrations of organochloride compounds in women from Flix, Tarragona [Spain]

open access: yesGaceta Sanitaria, 2003
La población de Flix (comarca de la Ribera del Ebro, Tarragona) se encuentra altamente expuesta a hexaclorobenceno (HCB) debido a la proximidad de una empresa electroquímica.
N. Ribas-Fitó   +3 more
doaj  

Quantitative Choroid Plexus Gadolinium Enhancement Is Related to Diffuse Brain Tissue Injury in Multiple Sclerosis

open access: yesJournal of Neuroimaging, Volume 36, Issue 2, March/April 2026.
ABSTRACT Background Recent studies suggest that disruptions of the blood–cerebrospinal fluid (CSF) barrier within the choroid plexus (ChP) may contribute to multiple sclerosis (MS) pathogenesis. We investigated the relationship between a quantitative marker of ChP enhancement and markers of focal and diffuse brain tissue injury in MS.
Sneha Senthil   +10 more
wiley   +1 more source

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