Results 21 to 30 of about 55,181 (130)

Investigating the Link Between Objective Sleep Metrics and Cerebral Small Vessel Disease in a Population‐Based Cohort

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Cerebral small vessel disease (CSVD), a disorder that affects the cerebral microvasculature, is commonly associated with aging and may contribute to dementia and stroke. Increasing evidence suggests a link between CSVD and sleep disturbances, but the association remains poorly understood.
Mareike Ludwig   +11 more
wiley   +1 more source

Determinants of maximal oxygen uptake in highly trained females and males: a mechanistic study of sex differences using advanced invasive methods

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo   +11 more
wiley   +1 more source

Haloalkane Dehalogenase LinB is responsible for β- and δ-hexachlorocyclohexane transoformation in sphingobium indicum B90A

open access: yes, 2006
Incubation of resting cells of Sphingobium indicum B90A, Sphingobium japonicum UT26, and Sphingobium francense Sp+ showed that they were able to transform ß- and -hexachlorocyclohexane (ß- and -HCH, respectively), the most recalcitrant ...
Lal, R.   +28 more
core   +1 more source

Shared Spectral Parameters Between EEG and Basal Ganglia LFP Distinguish Sleep‐Specific Oscillations in Parkinson's Disease

open access: yesEuropean Journal of Neurology, Volume 33, Issue 9, September 2026.
In 19 people with Parkinson's disease and STN‐DBS, aperiodic features of cortical EEG and STN LFP tracked one another across full nights of polysomnography‐scored sleep. Aperiodic offset and slope distinguished wakefulness from sleep, and STN‐LFP features alone classified sleep stages as accurately as combined STN‐LFP and EEG.
Lisa Hirt   +11 more
wiley   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 7, July 2026.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng   +6 more
wiley   +1 more source

A Tutorial on Bayesian Multi‐Study Factor Analysis With Applications in Nutrition and Genomics

open access: yesStatistics in Medicine, Volume 45, Issue 10-12, May 2026.
ABSTRACT High‐dimensional data are crucial in biomedical research. Integrating such data from multiple studies is a critical process that relies on the choice of advanced statistical models, enhancing statistical power, reproducibility, and scientific insight compared to analyzing each study separately.
Mavis Liang   +3 more
wiley   +1 more source

Engineered Cellulose: A Multifunctional Platform for Next‐Generation Sustainable Environmental Technologies

open access: yesEcoMat, Volume 8, Issue 4, April 2026.
Engineered cellulose—enabled by functionalization, hybridization, and nano‐engineering—emerges as a versatile platform driving next‐generation solutions in water purification, CO2 capture, air filtration, soil remediation, energy storage, and sustainable packaging. ABSTRACT Engineered cellulose is redefining the frontier of sustainable materials in the
Amir Hossein Behroozi   +1 more
wiley   +1 more source

Characterisation of Aardvark, a Dictyostelium ß-catenin. [PDF]

open access: yes, 2003
Wnt signalling is active both in development and the progression of certain disease processes, most notably cancer. Glycogen Synthase Kinase-3 (GSK-3) and ß-catenin both define the canonical Wnt pathway, where GSK-3 negatively regulates ß-catenin ...
Reynolds, Jonathan Peter, Reynolds, JP
core  

Quantitative Choroid Plexus Gadolinium Enhancement Is Related to Diffuse Brain Tissue Injury in Multiple Sclerosis

open access: yesJournal of Neuroimaging, Volume 36, Issue 2, March/April 2026.
ABSTRACT Background Recent studies suggest that disruptions of the blood–cerebrospinal fluid (CSF) barrier within the choroid plexus (ChP) may contribute to multiple sclerosis (MS) pathogenesis. We investigated the relationship between a quantitative marker of ChP enhancement and markers of focal and diffuse brain tissue injury in MS.
Sneha Senthil   +10 more
wiley   +1 more source

Metabolomics of hexachlorocyclohexane (HCH) transformation: ratio of LinA to LinB determines metabolic fate of HCH isomers

open access: yes, 2013
Although the production and use of technical hexachlorocyclohexane (HCH) and lindane (the purified insecticidal isomer -HCH) are prohibited in most countries, residual concentrations still constitute an immense environmental burden. Many studies describe
Fleischmann, Thomas   +20 more
core   +1 more source

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