Results 11 to 20 of about 39,124 (129)
Mitophagy in Hypertensive Cardiac Hypertrophy: Mechanisms and Therapeutic Implications. [PDF]
ABSTRACT Hypertensive cardiac hypertrophy (HCH) is a compensatory response to chronic pressure overload, ultimately progressing to heart failure if left unmanaged. Emerging evidence highlights the critical role of mitochondrial dysfunction in HCH pathogenesis, with impaired mitophagy—a selective autophagic process that removes damaged mitochondria ...
Li S, Li X.
europepmc +2 more sources
CHB-Induced Immune Zonation Chaos Elicited LXRα-mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation. [PDF]
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Shi J +18 more
europepmc +2 more sources
Effects of irrigation with HCH-contaminated water on crop performance and HCH accumulation in plant and soil [PDF]
7 Pags.- 6 Tabls.Lindane production is very ineffective since, for each ton of lindane obtained, between 6 and 10 tons of hexachlorocyclohexane (HCH) isomers and other toxic compounds are produced.
Quílez Sáez de Viteri, Dolores +4 more
core +2 more sources
Hexabromocyclododecane and hexachlorocyclohexane: How lessons learnt have led to improved regulation [PDF]
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2014 Taylor & Francis.The use of chemicals by society has many benefits but contamination of the environment is an unintended consequence.
Onogbosele, CO, Scrimshaw, MD
core +1 more source
Modeling redistribution of α-HCH in Chinese soil induced by environment factors [PDF]
This study explores long-term environmental fate of alpha-HCH in China from 1952 to 2007 using ChnGPERM (Chinese Gridded Pesticide Emission and Residue Model).
Tian, Chongguo +10 more
core +1 more source
Assessing environmental fate of β-HCH in Asian soil and association with environmental factors [PDF]
Chinese Gridded Pesticide Emission and Residue Model was applied to simulate long-term environmental fate of beta-HCH in Asia spanning 1948-2009. The model captured well the spatiotemporal variation of beta-HCH soil concentrations across the model domain.
Tian, Chongguo +8 more
core +1 more source
The historical annual loading to, removal from, and cumulative burden in the Arctic Ocean for β-hexachlorocyclohexane (β-HCH), an isomer comprising 5–12% of technical HCH, is investigated using a mass balance box model from 1945 to 2020.
Roland Kallenborn +8 more
core +1 more source

