Results 11 to 20 of about 256,894 (159)

Mitophagy in Hypertensive Cardiac Hypertrophy: Mechanisms and Therapeutic Implications. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT Hypertensive cardiac hypertrophy (HCH) is a compensatory response to chronic pressure overload, ultimately progressing to heart failure if left unmanaged. Emerging evidence highlights the critical role of mitochondrial dysfunction in HCH pathogenesis, with impaired mitophagy—a selective autophagic process that removes damaged mitochondria ...
Li S, Li X.
europepmc   +2 more sources

The influence of organochlorine compound exposure on the physiological development of children [PDF]

The present study summarizes the advances on the knowledge of the health disturbances associated to fetal exposure to organochlorine compounds in a cohort of children from Menorca.
Grimalt, Joan O., Sunyer, Jordi, Torrent, Maties   +2 more
core   +1 more source

Evaluation of Ricinus communis L. for the Phytoremediation of Polluted Soil with Organochlorine Pesticides

BioMed Research International, 2015
Phytoremediation is an attractive alternative to conventional treatments of soil due to advantages such as low cost, large application areas, and the possibility of in situ treatment.
S. R. Rissato, M. S. Galhiane, J. Fernandes, M. Gerenutti, H. M. Gomes, R. Ribeiro, M. V. de Almeida   +6 more
semanticscholar   +1 more source

Umweltschadstoffe und Fertilität - Untersuchungen zum Einfluss endokrin wirksamer Chemikalien auf humane uterine Gewebe [PDF]

, 2011
Die ungestörte hormonelle Steuerung humaner Uterusschleimhaut (Endometrium) ist eine wesentliche Grundvoraussetzung der weiblichen Fertilität. Viele Untersuchungen haben bereits auf die große Komplexität Estrogen-vermittelter Signalwege, welche über zwei
Willing, Cornelia
core   +1 more source

FGFR3 mutation frequency in 324 cases from the International Skeletal Dysplasia Registry

Molecular Genetics & Genomic Medicine, 2014
Fibroblast growth factor receptor 3 (FGFR3) is the only gene known to cause achondroplasia (ACH), hypochondroplasia (HCH), and thanatophoric dysplasia types I and II (TD I and TD II). A second, as yet unidentified, gene also causes HCH. In this study, we
Yuan Xue, A. Sun, P. Mekikian, Jorge H. Martin, D. Rimoin, R. Lachman, W. Wilcox   +6 more
semanticscholar   +1 more source

Aqueous Zinc‐Based Batteries: Active Materials, Device Design, and Future Perspectives

Advanced Energy Materials, EarlyView.
This review conducts a comprehensive analysis of aqueous zinc‐based batteries (AZBs) based on their intrinsic mechanisms, including redox reactions, ion intercalation reactions, alloying reactions, electrochemical double‐layer reactions, and mixed mechanisms, systematically discussing recent advancements in each type of AZBs.
Yan Ran, Fang Dong, Shuhui Sun, Yong Lei
wiley   +1 more source

sEEG‐guided responsive neurostimulation to treat neocortical epilepsy: A multicenter retrospective study of the efficacy and safety of depth electrode‐mediated neuromodulation

Epilepsia Open, EarlyView.
Abstract Objectives Pivotal trials have established the effectiveness of the Responsive Neurostimulation System (RNS® System) in treating focal epilepsy. In clinical trials, depth leads were primarily used to treat mesial temporal seizure onsets while cortical strip leads were used to treat neocortical seizure onsets.
Sina Sadeghzadeh, David A. Purger, Priya Bhanot, Noriah Johnson, Daniel A. N. Barbosa, Yuhao Huang, Jay J. Park, Ethan Schonfeld, Matthew A. Abikenari, Bhav Jain, Joshua P. Aronson, Cornelia Drees, Tiffany L. Fisher, Jason Gerrard, Tyler E. Gray, Saadi Ghatan, Kevin Hines, Barbara C. Jobst, Ioannis Karakis, Steven G. Ojemann, Imran H. Quraishi, Ahmed M. Raslan, Michael D. Sather, Christopher T. Skidmore, Jon T. Willie, Chengyuan Wu, Ji Yeoun Yoo, Kevin D. Graber, Casey H. Halpern, Vivek P. Buch, Jonathon J. Parker   +30 more
wiley   +1 more source

Environmental chemicals in eggs of Eurasian Golden Plovers "Pluvialis apricaria" breeding in Lower Saxony: is reproduction endangered? [PDF]

, 2008
Aus dem niedersächsischen Brutgebiet Esterweger Dose wurden von 2003 bis 2006 18 Eier aus nicht oder nur teilweise geschlüpften Gelegen sowie die Lebern eines Embryos und eines Kükens des Goldregenpfeifers auf Rückstände an Umweltchemikalien untersucht ...
Becker, Peter H., Degen, Axel, Exo, Klaus-Michael, Pijanowska, Ursula   +3 more
core  

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng, Ling‐Li Chang, Hung‐Chen Wang, Wei‐Chun Hung, Chia‐Hua Hsieh, Yi‐Hsuan Wang, Kuang‐I Cheng   +6 more
wiley   +1 more source

Determinants of maximal oxygen uptake in highly trained females and males: a mechanistic study of sex differences using advanced invasive methods

The Journal of Physiology, EarlyView.
Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo, Marcos Martin‐Rincon, Bjarne Rud, Joachim Nielsen, Lars Henrik N. Hegg, Andreas V. Kleive, Niels Ørtenblad, Øyvind Sandbakk, Robert Boushel, Hans‐Christer Holmberg, Jose A.L. Calbet, Jostein Hallén   +11 more
wiley   +1 more source