Results 51 to 60 of about 916,602 (288)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Severe Accident Simulation of the Laguna Verde Nuclear Power Plant

open access: yesScience and Technology of Nuclear Installations, 2012
The loss-of-coolant accident (LOCA) simulation in the boiling water reactor (BWR) of Laguna Verde Nuclear Power Plant (LVNPP) at 105% of rated power is analyzed in this work. The LVNPP model was developed using RELAP/SCDAPSIM code.
Gilberto Espinosa-Paredes   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Statistics of zero crossings in rough interfaces with fractional elasticity [PDF]

open access: yes, 2017
We study numerically the distribution of zero crossings in one-dimensional elastic interfaces described by an overdamped Langevin dynamics with periodic boundary conditions.
Kolton, Alejandro Benedykt   +2 more
core   +4 more sources

Guía de buenas prácticas clínicas para la atención al niño con neumonía adquirida en la comunidad

open access: yesMedisur, 2019
La neumonía adquirida en la comunidad es frecuente en la edad pediátrica. El objetivo de este trabajo es exponer una guía de práctica médica, que sirva para abordar elementos sobre diagnóstico, epidemiología, etiología, factores de riesgos, clasificación
Daylin Madruga Jiménez   +3 more
doaj  

The utility of PET/CT with 18F-FDG in the study of Hodgkin's lymphoma and non-Hodgkin's lymphoma

open access: yesSaúde & Tecnologia, 2015
The lymphomas are tumors established in the lymphatic system. Due to their heterogeneity they can be classified as Hodgkin's lymphoma (HL) or non-Hodgkin's lymphoma (NHL), presenting each type of lymphoma, different prognosis and chemotherapeutic ...
Marta Milhões   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Study of the formation of Cu-24at.% Al by reactive milling [PDF]

open access: yes, 2015
In this work, powders of Cu and Al were milled with a proportion equal to 24 atomic % Al, using low and medium energy mills. The initial, intermediate and final stages of the resulting powder are analyzed using scanning electron microscopy, X-ray ...
Esquivel, Marcelo Ricardo Oscar   +4 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

An account on the taxonomy and molecular diversity of a marine rock-pool dweller, Tigriopus fulvus (Copepoda, Harpacticoida) [PDF]

open access: yes, 2019
The copepod genus Tigriopus Norman, 1869 is distributed worldwide in coastal rock pools and it is currently considered to include 14 valid species.
Eduardo Belda   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy