Results 71 to 80 of about 3,474,405 (252)

18F- FDG PET/CT IN MELANOMA OF PROBABLE ANORECTAL ORIGIN: CASE REPORT

Hematology, Transfusion and Cell Therapy
Introduction/Justification: Anorectal melanoma is a rare tumor that develops in melanin producing pigment cells of the anus and rectum. As a rare entity there is not much literature regarding the management of this pathology.
Felipe Piccarone Gonçalves Ribeiro, Thiago Ferreira de Souza, Dihego Ferreira dos Santos, Allan de Oliveira Santos, Mariana da Cunha Lopes de Lima, Elba Cristina Sá de Camargo Etchebehere, Celso Darío Ramos, Bárbara Juarez Amorim   +7 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Nuclear energy data 2010

, 2010
This 2010 edition of Nuclear Energy Data , the OECD Nuclear Energy Agency's annual compilation of official statistics and country reports on nuclear energy, provides key information on plans for new nuclear plant construction, nuclear fuel cycle ...
Agency, Nuclear Energy
core  

Prognostic Value of Adaptive Textural Features–The Effect of Standardizing Nuclear First-Order Gray Level Statistics and Mixing Information from Nuclei Having Different Area

Cellular Oncology, 2006
Background: Nuclear texture analysis is a useful method to obtain quantitative information for use in prognosis of cancer. The first-order gray level statistics of a digitized light microscopic nuclear image may be influenced by variations in the image ...
Birgitte Nielsen, Håvard E. Danielsen
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Ferro-ligas [PDF]

, 1996
Periodicidade: IrregularPeríodo inicial e final de publicação: jan./ago. 1996A partir de nov./1996 passou a ser publicado pela Área de Operações Industriais 2: Gerência Setorial
Banco Nacional de Desenvolvimento Econômico e Social (Brasil). Área de Operações Industriais 2. Gerência Setorial 3
core   +1 more source

Avaliação das doses no cristalino de indivíduos ocupacionalmente expostos em um serviço de PET/CT

Brazilian Journal of Radiation Sciences, 2018
O objetivo do estudo é avaliar a dose recebida no cristalino pelo Indivíduo Ocupacionalmente Exposto (IOE) na área de PET/CT do Serviço de Medicina Nuclear (SMN) de um Hospital Escola público de porte especial, determinando a necessidade, ou não, da ...
Andréia Caroline Fischer da Silveira Fischer, Maryana Nunes Moreira, Alexandre Bacelar   +2 more
doaj   +1 more source