Results 61 to 70 of about 401,775 (204)
Les scandaleuses libertés du style lascif dans l’Adone de Marino
Italies, 2007 L’article est consacré à l’immédiate réception de l’Adone (1623) et à la mise à l’Index de l’ouvrage (1627). Cette question est considérée sous deux aspects.
Danielle Boillet
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Advanced Science, EarlyView.Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu +9 more
wiley +1 more source
Advanced Science, EarlyView.The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen +15 more
wiley +1 more source
Advanced Science, EarlyView.This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang +21 more
wiley +1 more source
Introduction thématique : pour un tournant matériel des études sur la bande dessinée
Comicalités, 2019 À l’heure où la bande dessinée numérique fait émerger de nouvelles matérialités, il paraît crucial de repenser les supports de la bande dessinée dans toute leur diversité.
Bounthavy Suvilay, Sylvain Lesage
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Interfaces Numériques, 2018 Poussées par l’évolution des usages, les chaînes historiques de télévision ont engagé depuis 2009 la publication de leurs applications sur les smartphones.
Virginie Sonet
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Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Comicalités, 2012 Within the humoristic press that appeared in Spain at the beginning of the seventies, the El Papus journal (1973-1986) stands out for its taste for provocation and transgression of all social, political and cultural taboos of that time.
Marine Lopata
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Advanced Science, EarlyView.Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian +13 more
wiley +1 more source
Italies, 2010 Il fine di questo articolo è analizzare come la rappresentazione letteraria di scrittori maghrebini contribuisce in Italia alla costruzione simbolica dell’immaginario dei migranti.
Paola Checcoli
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