Results 61 to 70 of about 1,628,604 (228)
Libros y lecturas en la España de Carlos II
E-Spania, 2018 Dans un pays où le roi avait appris à lire et à écrire fort tard, l’accès à la lecture et aux libres ne fut pas chose aisée pour la grande majorité de la population. L’analphabétisme généralisé et l’état désastreux de l’éducation n’ont pas été l’objet de
Ofelia Rey Castelao
doaj +1 more source
Catalogue édition Lucien [photo Lucien non créditée]
, 1912 Catalogue édition Lucien ; photo Lucien non créditée ; verso "L'instant des ...
Lucien Édition, ., Daphy, Éliane
core
Advanced Science, EarlyView.ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo +14 more
wiley +1 more source
Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity
Advanced Science, EarlyView.This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj +25 more
wiley +1 more source
Advanced Science, EarlyView.An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi +8 more
wiley +1 more source
, 1930 La Parisienne édition vous présente ses derniers succès [recueil grand format vente à la rue] ; illustration Jan Dumon ; imprimerie Mathey, 7 cité Hittorff, Paris ; en dépôt Batifol rue du Verbois ; La Parisienne 81 Faubourg Saint-Martin, Paris ...
La Parisienne Lorette Édition, . +1 more
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Introduction. Dans la fabrique du polar vert : écopoétique et ruralité
Belphégor, 2023 Alice Jacquelin, Juliette Peillon
doaj +1 more source
Advanced Science, EarlyView.Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai +10 more
wiley +1 more source
In Situ, 2013 Among the rare publications devoted to colonial housing in the West Indies and French Guyana, the manual titled “The Rustic House” (Maison rustique à l’usage des habitants de la partie de la France équinoxiale connue sous le nom de Cayenne) published in ...
Emilie d’Orgeix, Céline Frémaux
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Advanced Science, EarlyView.A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang +13 more
wiley +1 more source