Methylomic signature of lithium response in bipolar disorder [PDF]
Introduction Bipolar disorder (BD) is a chronic and severe psychiatric disorder, characterized by the alternance of episodes of (hypo)-mania and major depression.
C. Bourdon +4 more
doaj +2 more sources
Contextualizing aging clocks and properly describing biological age. [PDF]
Biological age is an abstract concept that helps explain how an individual is functionally aging. Given that aging is a remarkably complex and multifarious process, it is infeasible to quantify biological age with a single aging biomarker. Rather than conflating a given metric with biological age, it makes more sense to conceptualize aging biomarkers ...
Johnson AA, Shokhirev MN.
europepmc +2 more sources
Associations between circadian misalignment and telomere length in BD: an actigraphy study [PDF]
Background Life expectancy is significantly decreased in bipolar disorder (BD). This is associated with accelerated cellular aging which can be estimated by telomere length (TL). However, specific determinants of shorter TL in BD are under-explored. This
Luana Spano +5 more
doaj +2 more sources
Methylomic biomarkers of lithium response in bipolar disorder: a clinical utility study [PDF]
Background Response to lithium (Li) is highly variable in bipolar disorders (BD). Despite decades of research, no clinical predictor(s) of response to Li prophylaxis have been consistently identified.
C. Marie-Claire +6 more
doaj +2 more sources
Correction to: Using density of antecedent events and trajectory path analysis to investigate family-correlated patterns of onset of bipolar I disorder: a comparison of cohorts from Europe and USA [PDF]
Jan Scott +4 more
doaj +2 more sources
This paper outlines the interdependency between arts and technology, and explains the absolute necessity of keeping them together in our education systems.
Etain Watson
doaj +1 more source
Insomnia and circadian rhythm: a bibliometrics study and visualization analysis via CiteSpace
ObjectiveThe present study aimed to use CiteSpace to analyze the status of insomnia and circadian rhythm, identify the hot spots and trends, and provide a basis for future study.MethodThe Web of Science database was searched for studies related to ...
Qing-Yun He +7 more
doaj +1 more source
Physical and mental health status of former smokers and non‐smokers patients with bipolar disorder
Abstract Objectives Up to 70% individuals with bipolar disorder (BD) are lifetime tobacco smokers, a major modifiable risk factor for morbidity. However, quitting smoking is rarely proposed to individuals with BD, mainly because of fear of unfavorable metabolic or psychiatric changes.
Bénédicte Nobile +25 more
wiley +1 more source
The Future of Northern Ireland: the Role of the Belfast/Good Friday Agreement Institutions
Abstract Since the 2016 Brexit referendum a series of crises has gripped Northern Ireland's politics. This has had a destabilising effect across society, which has arguably been felt most acutely by political unionism. The Belfast/Good Friday Agreement (B/GFA) of 1998 created a series of institutions to deal with political conflict in Northern Ireland,
Conor J. Kelly, Etain Tannam
wiley +1 more source
Abstract Objectives Persistent functional impairment is common in bipolar disorder (BD) and is influenced by a number of demographic, clinical, and cognitive features. The goal of this project was to estimate and compare the influence of key factors on community function in multiple cohorts of well‐characterized samples of individuals with BD.
Katherine E. Burdick +49 more
wiley +1 more source

