Results 121 to 130 of about 4,501,314 (250)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Évaluation et didactique des mathématiques : vers de nouvelles questions, de nouveaux travaux
, 2018 Les travaux sur l’évaluation dans ses différents aspects sont nombreux et les entrées sont diverses (docimologie, évaluations internationales, évaluation formative, effets sur la motivation, liens avec l’orientation des élèves, etc.).
Sylvie Coppé, Coppé, Sylvie
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
“ J’ai fait fermer U Express ”
, 2019 “J’ai fait fermer U express”Réinjecter de l’évaluation dans la manutention ordinaireArchives augmentées de la présentation du lundi 13 mai 2019 : Évaluation générale.
guiller
core
GlossaContexte : La compréhension verbale est une composante clé du développement du langage. Or, cette composante est particulièrement déficitaire chez les enfants avec Trouble du Spectre Autistique (TSA) et déficience intellectuelle (DI).
Charline Grossard
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
, 2006 L'objet de cette pré-évaluation est d'établir un premier diagnostic de « l'utilisabilité » et de « l'acceptabilité » par les conducteurs de l'assistance proposée par le système LAVIA et de fournir des recommandations méthodologiques pour la collecte et l'
Dionisio, C., Saad, Faten
core +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source