Results 141 to 150 of about 4,791,418 (250)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Epidemiology and Characterization of Immunological Disorders in Children Diagnosed With Pneumococcal Invasive Disease. [PDF]
Int J PediatrShahar C +3 more
europepmc +1 more source
, 2012 Annexe du rapport finalThe table of contents for this item can be shared with the requester. The requester may then choose one chapter, up to 10% of the item, as per the Fair Dealing provision of the Canadian Copyright ...
Association Marocaine de l'Évaluation
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Rapport annuel sur l'évaluation 2006
, 2006 Version anglaise disponible dans la Bibliothèque numérique du CRDI: Annual corporate evaluation report ...
CRDI. Section de l'évaluation
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Rapport annuel sur l'évaluation 1994
, 1994 Version anglaise disponible dans la Bibliothèque numérique du CRDI: Annual corporate evaluation report ...
CRDI. Section de l'évaluation
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Toward a mixed-methods framework for evaluating digital health systems in low-resource settings: an infrastructure-aware perspective. [PDF]
Front Digit HealthNyatuka RD, Cherinet P, Jabin MSR.
europepmc +1 more source
Rapport annuel sur l'évaluation 1995
, 1995 Version anglaise disponible dans la Bibliothèque numérique du CRDI: Annual corporate evaluation report ...
CRDI. Section de l'évaluation
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