Results 151 to 160 of about 4,791,418 (250)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

A pilot study to implement artificial intelligence-enabled, point-of-care obstetric ultrasound for gestational age estimation in Zambia: An evaluation protocol. [PDF]

PLoS One
Gazzetta E, Matenga TFL, Martin S, Mandona N, Barada R, Chileshe M, Stringer E, Chinyama M, Chembo B, Chi H, Mwiche A, Ng'anjo S, Stringer JSA, Chi BH, Kasaro M.   +14 more
europepmc   +1 more source

Constatations en bref de l'examen externe du programme Droits des femmes et participation citoyenne (DFPC)

, 2010
Version anglaise disponible dans la Bibliothèque numérique du CRDI: Findings brief : external review of the Women's Rights and Citizenship ProgramCe texte présente les principales constatations du rapport intitulé Women's Rights and ...
CRDI. Section de l'évaluation
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Introduction

Revue Internationale d’Éducation de Sèvres, 1996
Josette Le Coq, Jacqueline Levasseur
doaj   +1 more source

Constatations en bref de l'examen externe du programme Paix, conflits et développement

, 2010
Version anglaise disponible dans la Bibliothèque numérique du CRDI: Findings brief : external review of the Peace, Conflict andCe texte présente les principales constatations des rapports intitulés External Review of IDRC's Peace, Conflict, and ...
CRDI. Section de l'évaluation
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Construction and application of connection number and projection pursuit models for groundwater quality evaluation: A case study of the main urban area of Bozhou City. [PDF]

PLoS One
Li Z, Jiang S, Jin J, Shen R, Yuan H.
europepmc   +1 more source

Rapport annuel sur l'évaluation 2010-2011

, 2011
Version anglaise disponible dans la Bibliothèque numérique du CRDI: Annual corporate evaluation report 2010 ...
CRDI. Section de l'évaluation
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source