Results 161 to 170 of about 4,791,418 (250)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Outcomes, Evaluation Metrics, and Measurement Tools for Large Language Model Applications Research in Nursing: A Scoping Review. [PDF]
Int Nurs RevLin Z +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Evaluation of LLMs for Automated Dental-to-Medical Consult Letter Generation: Comparative Study. [PDF]
Int Dent JEom D, Koh K, Chung H, Kim K, Lee SH.
europepmc +1 more source
Rapport annuel sur l'évaluation 2011-2012
, 2012 Version anglaise disponible dans la Bibliothèque numérique du CRDI: Annual corporate evaluation report 2011 ...
CRDI. Section de l'évaluation
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Nursing students' perceptions and experiences of student-lecturer evaluation as a strategy for improving teaching and learning at the University of Namibia. [PDF]
CurationisStanislaus RK, Ashipala DO, Amadhila J.
europepmc +1 more source