Results 111 to 120 of about 8,743,550 (229)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Œdème pulmonaire à pression négative. [PDF]
CMAJLemyze M, Granier M, Marshall DC.
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
LE PEAGE URBAIN : UNE SOURCE DE FINANCEMENT ACCEPTABLE ? AVEC UNE APPLICATION AU CAS DE L’AGGLOMERATION STRASBOURGEOISE [PDF]
Après avoir brièvement rappelé les raisons par lesquelles la théorie économique justifie traditionnellement le recours au péage urbain, l’article examine les principaux éléments qui expliquent les résistances des agents économiques, afin d’en comprendre ...
Damien Broussolle
core
, 2016 Contamination des eaux de surface par les pesticides : extension et évaluation d’un outil d’évaluation de la part des apports ...
Lecuyer, Vanessa +10 more
core +1 more source
Artificial intelligence and the evaluation of scientific articles: promise and caution. [PDF]
Med Trop Sante IntSélarréché B.
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Proposition et réalisation d’une solution pour l’évaluation par les pairs dans les MOOCs.
, 2017 94 f. : ill. ; 30 cm. (+ CD-Rom)Au cours des six dernières années une nouvelle forme d'enseignement à distance est apparue appelé MOOC (Massive Open Online Courses).
Kacer Aissa, Mesbah Elghani
core
Réaction d’hypersensibilité aux agents de contraste iodés. [PDF]
CMAJJeimy S, Kassam Z, Copaescu AM.
europepmc +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source