Results 101 to 110 of about 2,022,448 (287)

Making best use of model evaluations to compute sensitivity indices

, 2002
This paper deals with computations of sensitivity indices in sensitivity analysis. Given a mathematical or computational model y=f(x1,x2,…,xk), where the input factors xi's are uncorrelated with one another, one can see y as the realization of a ...
Andrea Saltelli
semanticscholar   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The future of biotic indices in the ecogenomic era: Integrating (e)DNA metabarcoding in biological assessment of aquatic ecosystems.

Science of the Total Environment, 2018
The bioassessment of aquatic ecosystems is currently based on various biotic indices that use the occurrence and/or abundance of selected taxonomic groups to define ecological status.
J. Pawłowski, M. Kelly‐Quinn, F. Altermatt, L. Apothéloz-Perret-Gentil, P. Beja, A. Boggero, Á. Borja, A. Bouchez, T. Cordier, I. Domaizon, M. Feio, A. Filipe, R. Fornaroli, W. Graf, Jelger Herder, B. B. van der Hoorn, J. I. Jones, M. Ságová-Marečková, Christian Moritz, J. Barquín, J. Piggott, Maurizio Pinna, F. Rimet, B. Rinkevich, Carla Sousa‐Santos, V. Specchia, R. Trobajo, V. Vasselon, S. Vitecek, Jonas Zimmerman, A. Weigand, F. Leese, M. Kahlert   +32 more
semanticscholar   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Hipótese do caminho aleatório nos mercados da América Latina: aplicação do teste de quociente de variância [PDF]

, 2001
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro TecnológicoExistem poucos estudos sobre a dinâmica dos preços de títulos e comportamento aleatório nas variações para mercados emergentes da América Latina, e os que existem mostram ...
Ceretta, Paulo Sergio
core  

CARACTERIZACIÓN DE LAS SEQUÍAS EN LA LOCALIDAD DE TRES ARROYOS (1930-1975). APLICACIÓN DEL MÉTODO DE PALMER

Papeles de Geografí­a, 2002
En el presente trabajo se analizan los períodos de sequías de la localidad de Tres Arroyos, localizada en el sudeste de la provincia de Buenos Aires. El período de estudio corresponden a los años 1930-1975. Se utilizó el índice de Sequía de Palmer.
María Elizabeth Carbone, María Cintia Piccolo   +1 more
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Lógica difusa, distribución de especies y los índices de similitud en ecología [PDF]

, 2015
La biodiversidad de distintas regiones y la similitud entre patrones de distribución de especies y entre comunidades biológicas se miden habitualmente con índices que requieren datos de presencia y de ausencia de las especies.
Enes Barbosa, Ana Marcia
core  

Calidad de suelo en el cultivo de banano: evaluación, desafíos y oportunidades

Agronomía Costarricense
Introducción. El banano es una de las frutas más importantes a nivel mundial, tanto en términos de exportación como de consumo. Ocupa, aproximadamente, 12 millones de hectáreas en suelos tropicales y subtropicales del mundo.
Jose Pablo Vargas-Fernández, Lidieth Uribe-Lorío, Ronald Romero-Calderón, Jorge Armando Leiva-Sanabria   +3 more
doaj   +1 more source