Results 131 to 140 of about 1,797,947 (267)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Proyecto de elaboración de indices para medir la productividad de empresas del sector comercial especializadas en tiendas departamentales de moda [PDF]
, 2009 Desde el año 1919, el Ecuador ha dado acogida a un segmento muy particular en el sector comercial de la Economía, que ha dado cobertura a gran parte de las necesidades de los consumidores y consumistas pasando a formar parte fundamental y actualmente un ...
Cantos Proaño, Rosicler Ivon +2 more
core +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Construcción del índice de términos de intercambio para Colombia [PDF]
El documento compara tres índices alternativos para la medición de los Términos de Intercambio (TI) en Colombia: el ITI-PIB, que se construye con los deflactores implícitos del PIB; el ITI-CE, que utiliza el índice de valor unitario con información de ...
Aarón L.Garavito Acosta +4 more
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FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Avaliação da qualidade da água das ribeiras Odelouca, Odeleite e Foupana (Algarve, Portugal): uso de macroinvertebrados bentónicos como bioindicadores [PDF]
, 2009 São várias as perturbações antropogénicas que afectam os rios e as ribeiras em Portugal, razão pela qual é urgente a implementação de medidas que visem a sua protecção.
Máximo, Isa Brioso
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FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Metodologias de índices para análise da sustentabilidade em bacias hidrográficas. [PDF]
, 2016 A manutenção da quantidade e qualidade dos recursos hídricos é um desafio a ser equacionado na atualidade, tendo em vista que este recurso é indispensável para diversas formas de vida na terra.
CRUZ, M. A. S. +2 more
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