Results 51 to 60 of about 42,577,972 (281)

Distinct Molecular Pathways Supporting Sjögren Disease Clusters and Disease Progression

Arthritis &Rheumatology, EarlyView.
Objective Sjögren disease (SjD) is a heterogeneous autoimmune disease. We aimed to investigate blood transcriptomic signatures and disease progression among three recently defined clusters of patients with SjD: (1) B cell active disease with low symptom burden (BALS), (2) high systemic activity (HSA), and (3) low systemic activity with high symptom ...
Sacha E. Silva‐Saffar, Yann Nguyen, Raphaèle Seror, Jacques‐Eric Gottenberg, Anna Niarakis, Xavier Mariette, Gaetane Nocturne   +6 more
wiley   +1 more source

Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The high cost of cultivation media remains one of the barriers to the commercialization of cultivated meat. Current serum‐free media reduce reliance on fetal bovine serum but only achieve modest cost savings. Especially at larger scales (> 20 m3), pharmaceutical‐grade amino acids and recombinant proteins remain major cost drivers.
Jelle C. Hoek, Jean‐Marc Daran, Marieke E. Klijn, Marcel A. Vieira‐Lara   +3 more
wiley   +1 more source

Plan de conservation en Île-de-France : Linaria pelisseriana (L.) Mill., 1768 (Linaire de Pélissier) [PDF]

, 2018
Dans le cadre de sa stratégie de conservation concernant les espèces rares et menacées d’extinction sur son territoire d’agrément, le CBN du Bassin parisien rédige des Plans de conservation pour les espèces les plus prioritaires dont le maintien des ...
Salvaudon, Clémence
core  

IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: implications for antimetastatic treatment

Journal for ImmunoTherapy of Cancer, 2020
Background As the immune system is compromised in patients with cancer, therapeutic strategies to stimulate immunity appear promising, to avoid relapse and increase long-term overall survival.
Mélanie Desbois, Coralie Béal, Mélinda Charrier, Benjamin Besse, Guillaume Meurice, Nicolas Cagnard, Yannick Jacques, David Béchard, Lydie Cassard, Nathalie Chaput   +9 more
doaj   +1 more source

Sex Differences in Social, Health, and Lifestyle Characteristics Associated With Binge‐Eating Behaviors: Results From a French National Random Population‐Based Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To explore sex differences in social, health and lifestyle characteristics associated with binge‐eating behaviors in a large population‐based study. Method This study included 84,995 participants (women 52.1%) aged ≥ 15 years from the French national random population‐based EpiCov cohort.
Junko Kose, Nathalie Godart, Anne Pastorello, Caroline Huas, Alexandra Rouquette, EpiCov Study Group, Josiane Warszawski, Nathalie Bajos, Guillaume Bagein, François Beck, Emilie Counil, Florence Jusot, Nathalie Lydié, Claude Martin, Laurence Meyer, Philippe Raynaud, Alexandra Rouquette, Ariane Pailhé, Delphine Rahib, Patrick Sillard, Rémy Slama, Alexis Spire   +21 more
wiley   +1 more source

Plan de conservation en Île-de-France : Sedum hirsutum All., 1785 [PDF]

, 2018
Dans le cadre de sa stratégie de conservation concernant les espèces rares et menacées d’extinction sur son territoire d’agrément, le CBN du Bassin parisien rédige des Plans de conservation pour les espèces les plus prioritaires dont le maintien des ...
Lehane, Fiona, Potier, Alexandra
core  

Impact of the presence of a prosthetic implant and transition to oral stepdown therapy on relapse rates and mortality in uncomplicated Staphylococcus aureus bacteremia treated with 14 days of antibiotics: a retrospective cohort study

Microbiology Spectrum
The aim of this single-center, retrospective observational study was to evaluate the effects of having a prosthetic implant (PI) and of changing from intravenous to oral antibiotics (oral stepdown therapy [OST]) on the risk of relapse in patients with ...
Damien Blez, Luc Labarbe, Patrick Grohs, Jean-Luc Mainardi, Jean-Philippe Barnier, David Lebeaux, Marie Dubert   +6 more
doaj   +1 more source

The Synthesis Use of a Difluorinated Amino‐Benzo‐Cinnoline Dyes (ABCDyes) Enables Fine Tuning of Emission Through Double SNAr Late‐Stage Functionalization

European Journal of Organic Chemistry, EarlyView.
An efficient synthesis of difluorinated amino‐benzo‐cinnoline dyes (ABCDyes) is reported. Their use for the late‐stage introduction of internal dinucleophilic species through a double SNAr reaction enables straightforward access to previously unexplored ABCDye analogs displaying tunable emission ranging from green to red.
Mélina Fabe, Narjis Ouazzani, Max Coehlo, Arnaud Chevalier   +3 more
wiley   +1 more source

Plan de conservation en Île-de-France : Carex mairei Coss. & Germ., 1840 (Laîche de Maire) [PDF]

, 2016
Dans le cadre de sa stratégie de conservation concernant les espèces rares et menacées d’extinction sur son territoire d’agrément, le CBN du Bassin parisien rédige des Plans de conservation pour les espèces les plus prioritaires dont le maintien des ...
Salvaudon, Clémence
core  

Central nervous system tumours and occupational ionising radiation exposure: a nested case–control study among the ORICAMs cohort of healthcare workers in France

BMJ Open
Objective This study aimed at investigating the relationship between occupational exposure to external ionising radiation and central nervous system (CNS) tumours mortality in healthcare workers working in France.Design and setting The Occupational ...
Sylvaine Caër-Lorho, Klervi Leuraud, Marie-Odile Bernier, Lynda Bensefa-Colas, Julie Lopes, Clémence Baudin, Frédéric Rousseau, Hervé Roy, Philippe Lestaevel   +8 more
doaj   +1 more source